This gene encodes a member of the alcohol dehydrogenase family. The encoded protein is the alpha subunit of class I alcohol dehydrogenase, which consists of several homo- and heterodimers of alpha, beta and gamma subunits. Alcohol dehydrogenases catalyze the oxidation of alcohols to aldehydes. This gene is active in the liver in early fetal life but only weakly active in adult liver. This gene is found in a cluster with six additional alcohol dehydrogenase genes, including those encoding the beta and gamma subunits, on the long arm of chromosome 4. Mutations in this gene may contribute to variation in certain personality traits and substance dependence. [provided by RefSeq, Nov 2010]
产品应用
应用
已检合格种属
预测种属
推荐稀释比例
WB
Rat
Human, Mouse
1:500-2000
IHC-P
Human, Mouse, Rat
1:100-500
IHC-F
Human, Mouse, Rat
1:400-800
IF
Human, Mouse, Rat
1:100-500
ICC/IF
Human, Mouse, Rat
1:50-100
交叉反应
交叉反应: Human, Mouse, Rat
相关产品
暂无相关产品
靶标
基因名
ADH1A
蛋白名
Alcohol dehydrogenase 1A
亚细胞定位
Cytoplasmic.
相似性
Belongs to the zinc-containing alcohol dehydrogenase family.