CD2重组兔单抗

bsm-60313R

重组兔单抗

CD2 Recombinant Rabbit mAb

CD2重组兔单抗

LFA-2; SRBC; T11; Ly-37; Ly37; CD2R; LFA2; OX-34; OX34; CD2_HUMAN; CD2; Erythrocyte receptor; LFA-3 receptor; Rosette receptor; T-cell surface antigen T11/Leu-5; CD2_MOUSE; Lymphocyte antigen 37 (Ly-37); CD2_RAT; OX-34 antigen;

Rabbit

KLH conjugated synthetic peptide derived from human CD2

IgG

Liquid

affinity purified by Protein A

Recombinant

C11G5

37 kDa

1mg/ml

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

CD2分子又称T11、绵羊红细胞受体（ER）、淋巴细胞功能相关抗原2（LFA-2）和Leu5，是人T淋巴细胞表面的单链糖蛋白.CD2分子是分布于胸腺细胞及所有成熟T淋巴细胞和大部分自然杀伤细胞表面的特征性分化抗原。CD2具有调节T淋巴细胞分化、成熟、激活和凋亡等功能，CD2与LFA-3之间的粘附功能对于T淋巴细胞TCR识别外来抗原与APC细胞表面MHC抗原复合物、肿瘤抗原、病毒感染靶细胞以及同种异体抗原均有重要的辅助作用。
最近研究表明，CD48和CD59也是CD2的配体，参与T细胞的粘附和细胞间的相互作用,此外，CD2可以与其它膜分子如CD44、CD45的功能有关。CD2具有对T细胞的旁路激活途径作用。

The protein encoded by this gene is a surface antigen found on all peripheral blood T-cells. The encoded protein interacts with LFA3 (CD58) on antigen presenting cells to optimize immune recognition. A locus control region (LCR) has been found in the 3' flanking sequence of this gene. [provided by RefSeq, Jun 2016]