整合素αE重组兔单抗

Rrmab®兔单抗
2026-01-04~2026-02-28,RR26012026-01-04~2026-02-28,TR
整合素αE重组兔单抗
货号:bsm-60226R
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概述

产品编号
bsm-60226R
产品类型
重组兔单抗、mIHC精品抗体
英文名称
ITGAE/CD103 Recombinant Rabbit mAb
中文名称
整合素αE重组兔单抗
英文别名
CD103; HUMINAE; ITAE_HUMAN; ITGAE; HML-1 antigen; Integrin alpha-IEL; Mucosal lymphocyte 1 antigen;
抗体来源
Rabbit
免疫原
KLH conjugated synthetic peptide derived from human ITGAE/CD103
亚型
IgG
性状
Liquid
纯化方法
affinity purified by Protein A
克隆类型
Recombinant
克隆号
C4G1
理论分子量
110/128 kDa
浓度
1mg/ml
储存液
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
SWISS
Gene ID
保存条件
Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
背景资料
Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes an I-domain-containing alpha integrin that undergoes post-translational cleavage in the extracellular domain, yielding disulfide-linked heavy and light chains. In combination with the beta 7 integrin, this protein forms the E-cadherin binding integrin known as the human mucosal lymphocyte-1 antigen. This protein is preferentially expressed in human intestinal intraepithelial lymphocytes (IEL), and in addition to a role in adhesion, it may serve as an accessory molecule for IEL activation. [provided by RefSeq, Jul 2008]
整合素αE重组兔单抗整合素αE重组兔单抗整合素αE重组兔单抗

产品应用

应用已检合格种属预测种属推荐稀释比例
IHC-PHuman1:50-200
IHC-FHuman1:50-200
IFHuman1:50-200

交叉反应

交叉反应: Human

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靶标

基因名
ITGAE
蛋白名
Integrin alpha-E
亚基
Heterodimer of an alpha and a beta subunit. The alpha subunit is composed of an heavy and a light chains linked by a disulfide bond. Alpha-E associates with beta-7.
亚细胞定位
Membrane; Single-pass type I membrane protein.
组织特异性
Expressed on a subclass of T-lymphocytes known as intra-epithelial lymphocytes which are located between mucosal epithelial cells.
相似性
Belongs to the integrin alpha chain family.
Contains 7 FG-GAP repeats.
Contains 1 VWFA domain.
功能
Integrin alpha-E/beta-7 is a receptor for E-cadherin. It mediates adhesion of intra-epithelial T-lymphocytes to epithelial cell monolayers.

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