谷胱甘肽硫转移酶pi重组兔单抗

bsm-60581R

重组兔单抗、病理级抗体

GSTP1 Recombinant Rabbit mAb

谷胱甘肽硫转移酶pi重组兔单抗

DFN7; FAEES3; GST3; GSTP; HEL-S-22; PI; GSTP1_HUMAN; GSTP1; GST class-pi; GSTP1-1; 2.5.1.18;

Rabbit

A synthesized peptide derived from human GSTP1: 100-201

IgG

Liquid

affinity purified by Protein A

Recombinant

E7F9

23 kDa

1mg/ml

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

GST-Pi是GST家族中的一种主要的同工酶，广泛存在于全身器官中，尤以肝肾含量高，具有解毒功能。在多种肿瘤中高表达。目前认为是肿瘤细胞产生耐药的一种标记，与肿瘤的耐药（阿霉素、顺铂、氮芥、环磷酰胺和瘤可宁等）有关。该抗体主要用于细胞耐药方面的研究。

Glutathione S-transferases (GSTs) are a family of enzymes that play an important role in detoxification by catalyzing the conjugation of many hydrophobic and electrophilic compounds with reduced glutathione. Based on their biochemical, immunologic, and structural properties, the soluble GSTs are categorized into 4 main classes: alpha, mu, pi, and theta. This GST family member is a polymorphic gene encoding active, functionally different GSTP1 variant proteins that are thought to function in xenobiotic metabolism and play a role in susceptibility to cancer, and other diseases. [provided by RefSeq, Jul 2008]