BRD2蛋白重组兔单抗
Rrmab®兔单抗
货号：bsm-54434R
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概述
产品编号
bsm-54434R
产品类型
重组兔单抗
英文名称
BRD2 Recombinant Rabbit mAb
中文名称
BRD2蛋白重组兔单抗
英文别名
BRD2-IT1; D6S113E; FSH; FSHRG1; FSRG1; NAT; O27.1.1; RING3; RNF3; D17H6S113E; Frg-1; Fsrg-1; mKIAA4005; BRD2_HUMAN; BRD2; KIAA9001; BRD2_MOUSE; Female sterile homeotic-related protein 1 (Fsrg-1); Kiaa4005; BRD2_RAT; Protein RING3;
抗体来源
Rabbit
免疫原
A synthesized peptide derived from human BRD2: 1-55/801
亚型
IgG
性状
Liquid
纯化方法
affinity purified by Protein A
克隆类型
Recombinant
克隆号
R2A5
理论分子量
88 kDa
浓度
1mg/ml
储存液
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
研究领域
Cell Biology > Proteolysis / Ubiquitin > Proteasome / Ubiquitin > Ubiquitin E3 Enzymes > RING Finger E3 Ligase
Epigenetics and Nuclear Signaling > Bromodomains
Epigenetics and Nuclear Signaling > ChIP assays > ChIP antibodies
Epigenetics and Nuclear Signaling > Transcription > Bromodomain containing
Epigenetics and Nuclear Signaling > Transcription > Domain Families > Developmental Families
Signal Transduction > Protein Phosphorylation > Ser / Thr Kinases > Other Kinases
SWISS
Gene ID
保存条件
Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
数据库链接
背景资料
This gene encodes a transcriptional regulator that belongs to the BET (bromodomains and extra terminal domain) family of proteins. This protein associates with transcription complexes and with acetylated chromatin during mitosis, and it selectively binds to the acetylated lysine-12 residue of histone H4 via its two bromodomains. The gene maps to the major histocompatability complex (MHC) class II region on chromosome 6p21.3, but sequence comparison suggests that the protein is not involved in the immune response. This gene has been implicated in juvenile myoclonic epilepsy, a common form of epilepsy that becomes apparent in adolescence. Multiple alternatively spliced variants have been described for this gene. [provided by RefSeq, Dec 2010]
产品应用
| 应用 | 已检合格种属 | 预测种属 | 推荐稀释比例 |
|---|---|---|---|
| WB | Human | 1:500-2000 | |
| IHC-P | Human | 1:100-500 | |
| IHC-F | Human | 1:100-500 | |
| IF | Human | 1:100-500 | |
| Flow-Cyt | Human | 1:50-100 | |
| ICC/IF | Human | 1:50-200 |
交叉反应
交叉反应: Human
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靶标
基因名
BRD2
蛋白名
Bromodomain-containing protein 2
亚基
Homodimer. Interacts with E2F1 and with histone H4acetylated at 'Lys-13'.
亚细胞定位
Nucleus.
相似性
Contains 2 bromo domains.
Contains 1 ET domain.
Contains 1 ET domain.
功能
May play a role in spermatogenesis or folliculogenesis.
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