翻译延伸因子EF-1a重组兔单抗
Rrmab®兔单抗
货号：bsm-60686R
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概述
产品编号
bsm-60686R
产品类型
重组兔单抗
英文名称
EEF1A1 Recombinant Rabbit mAb
中文名称
翻译延伸因子EF-1a重组兔单抗
英文别名
CCS-3; CCS3; EE1A1; EEF-1; EEF1A; EF-Tu; EF1A; EF1A1; EF1alpha1; GRAF-1EF; LENG7; PTI1; eEF1A-1; Eef1a2; Eef1a2l1; SI; EF1A1_HUMAN; EEF1A1; EF-1-alpha-1; Elongation factor Tu (EF-Tu); Eukaryotic elongation factor 1 A-1 (eEF1A-1); Leukocyte receptor cluster member 7; 3.6.5.-; EF1A1_MOUSE; EF1A1_RAT;
抗体来源
Rabbit
免疫原
KLH conjugated synthetic peptide derived from human eEF1a1
亚型
IgG
性状
Liquid
纯化方法
affinity purified by Protein A
克隆类型
Recombinant
克隆号
R8F9
理论分子量
50 kDa
浓度
1mg/ml
储存液
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
研究领域
SWISS
Gene ID
保存条件
Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
数据库链接
产品介绍
肽链延长因子1A-1(peptide elongation factor 1A-1,eEF1A-1)是真核细胞蛋白翻译过程中肽链延长复合物的重要构成成分,具有调节蛋白合成及促发凋亡等多种作用.
背景资料
This gene encodes an isoform of the alpha subunit of the elongation factor-1 complex, which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. This isoform (alpha 1) is expressed in brain, placenta, lung, liver, kidney, and pancreas, and the other isoform (alpha 2) is expressed in brain, heart and skeletal muscle. This isoform is identified as an autoantigen in 66% of patients with Felty syndrome. This gene has been found to have multiple copies on many chromosomes, some of which, if not all, represent different pseudogenes. [provided by RefSeq, Jul 2008]
产品应用
| 应用 | 已检合格种属 | 预测种属 | 推荐稀释比例 |
|---|---|---|---|
| WB | Human, Mouse, Rat | 1:500-2000 | |
| IHC-P | Human, Mouse, Rat | 1:50-200 | |
| IHC-F | Human, Mouse, Rat | 1:50-200 | |
| IF | Human, Mouse, Rat | 1:50-200 | |
| ICC/IF | Human | Mouse, Rat | 1:50-200 |
交叉反应
交叉反应: Human, Mouse, Rat
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靶标
基因名
EEF1A1
蛋白名
Elongation factor 1-alpha 1
亚细胞定位
Cytoplasm.
组织特异性
Brain, placenta, lung, liver, kidney, pancreas but barely detectable in heart and skeletal muscle
翻译后修饰
ISGylated.
相似性
Belongs to the GTP-binding elongation factor family. EF-Tu/EF-1A subfamily.
功能
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
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