NQO1 Recombinant Rabbit mAb (一抗) - WB,Flow-Cyt,ICC/IF | Bioss

bsm-52830R

重组兔单抗

NQO1 Recombinant Rabbit mAb

醌氧化还原酶重组兔单抗

DHQU; DIA4; DTD; NMOR1; NMORI; QR1; Nmo-1; Nmo1; Ox-1; Ox1; NADPH-d; NQO1_HUMAN; NQO1; Azoreductase; DT-diaphorase (DTD); Menadione reductase; NAD(P)H:quinone oxidoreductase 1; Phylloquinone reductase; Quinone reductase 1 (QR1); 1.6.5.2; NQO1_MOUSE; NQO1_RAT;

Rabbit

A synthesized peptide derived from human NQO1: 1-46/274

IgG

Liquid

affinity purified by Protein A

Recombinant

8T5

31 kDa

31 kDa

1mg/ml

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

合成与降解（Synthesis and Degradation）
醌氧化还原酶（NQO1）是一种黄素酶，它催化醌双电子还原反应，以减少氧自由基的产生。经研究发现NQO1可能有抗氧化效应，目前多用于帕金森病（PD）和部分肿瘤方面的研究。
醌是一种有毒的化合物,能诱发哺乳动物细胞癌变、突变和坏死。

This gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer's disease (AD). Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq].