双特异性蛋白磷酸酶6重组兔单抗

bsm-52270R

重组兔单抗、mIHC精品抗体

DUSP6 Recombinant Rabbit mAb

双特异性蛋白磷酸酶6重组兔单抗

HH19; MKP3; PYST1; 1300019I03Rik; MKP-3; DUS6_HUMAN; DUSP6; Dual specificity protein phosphatase PYST1; Mitogen-activated protein kinase phosphatase 3 (MAP kinase phosphatase 3 | MKP-3); 3.1.3.16; 3.1.3.48; DUS6_MOUSE; DUS6_RAT;

Rabbit

A synthesized peptide derived from human DUSP6: 351-381

IgG

Liquid

affinity purified by Protein A

Recombinant

9C3

42 kDa

1mg/ml

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK2, is expressed in a variety of tissues with the highest levels in heart and pancreas, and unlike most other members of this family, is localized in the cytoplasm. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]