SPHK2 Rabbit pAb (一抗) - WB,IHC-P,IHC-F,IF,ELISA | Bioss

2026-05-01~2026-06-30,AB2605
SPHK2 Rabbit pAb (一抗) - WB,IHC-P,IHC-F,IF,ELISA | Bioss
货号:bs-2653R
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概述

产品编号
bs-2653R
英文名称
SPHK2 Rabbit pAb
中文名称
鞘氨醇激酶2抗体
英文别名
SK 2; SK-2; SPK 2; SPK-2; Sk2; Spk2; SPHK2_HUMAN; SPHK2; 2.7.1.91; SPHK2_MOUSE; sphingosine kinase 2
抗体来源
Rabbit
免疫原
KLH conjugated synthetic peptide derived from human SPHK2: 101-200/654
亚型
IgG
性状
Liquid
纯化方法
affinity purified by Protein A
克隆类型
Polyclonal
理论分子量
72 kDa
检测分子量
68 kDa
浓度
1mg/ml
储存液
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
SWISS
Gene ID
保存条件
Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
背景资料
This gene encodes a kinase that phosphorylates sphingosine into sphingosine-1-phosphate, which is involved in cell differentiation, motility, and apoptosis. The encoded protein plays a role in maintaining cellular levels of sphingosine-1-phosphate. The gene product also enhances apoptosis in different cell types and suppresses cellular proliferation. In mast cells, the encoded protein is necessary for influx of calcium, protein kinase C activation, and cytokine production and degranulation. Alternative splicing results in multiple transcript variants. [provided by RefSeq].
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产品应用

应用已检合格种属预测种属推荐稀释比例
WBMouseHuman1:500-2000
IHC-PHuman, Mouse1:100-500
IHC-FHuman, Mouse1:100-500
IFHuman, Mouse1:100-500
ELISAHuman, Mouse1:5000-10000

交叉反应

交叉反应: Human, Mouse

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靶标

基因名
SPHK2
蛋白名
Sphingosine kinase 2
亚细胞定位
Isoform 1: Cytoplasm. Membrane. Isoform 2: Lysosome membrane.
相似性
Contains 1 DAGKc domain.
功能
Catalyzes the phosphorylation of sphingosine to form sphingosine 1-phosphate (SPP), a lipid mediator with both intra-and extracellular functions. Also acts on D-erythro-dihydrosphingosine, D-erythro-sphingosine and L-threo-dihydrosphingosine. Binds phosphoinositides.

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