Caspase-6重组兔单抗

bsm-52503R

重组兔单抗

Caspase-6 Recombinant Rabbit mAb

Caspase-6重组兔单抗

CSP-6; MCH2; caspase-6; CASP-6; CASP6_HUMAN; CASP6; Apoptotic protease Mch-2; 3.4.22.59; CASP6_MOUSE; CASP6_RAT;

Rabbit

A synthesized peptide derived from human Caspase 6: 150-293/293

IgG

Liquid

affinity purified by Protein A

Recombinant

10F5

33 kDa

1mg/ml

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

Caspase-6 与Caspase-3有38%的同源性，属胱氨酸-天冬氨酸蛋白酶家族。在凋亡执行阶段起中心作用，可被Caspase-7、-8、-10剪切。它是唯一一个可以剪切核纤层蛋白的Caspase。

This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein is processed by caspases 7, 8 and 10, and is thought to function as a downstream enzyme in the caspase activation cascade. Alternative splicing of this gene results in two transcript variants that encode different isoforms. [provided by RefSeq, Jul 2008]