钙结合蛋白重组兔单抗

bsm-54076R

重组兔单抗、病理级抗体

CALB2 Recombinant Rabbit mAb

钙结合蛋白重组兔单抗

CAB29; CAL2; CR; calb2; wu:fq17g09; zgc:73099; CALB2_CHICK; CALB2_HUMAN; 29 kDa calbindin; CALB2_MOUSE; CALB2_RAT;

Rabbit

A synthesized peptide derived from human Calretinin: 50-100

IgG

Liquid

affinity purified by Protein A

Recombinant

4A3

29 kDa

1mg/ml

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

钙结合蛋白(Calretinin,CR)主要存在于神经组织中，近10%的腺癌可以表达此蛋白的局部染色阳性，而绝大多数的间皮瘤为阳性表达，因此它是诊断间皮瘤的一个有用的标记物 。
钙结合蛋白是平滑肌和非肌性调控蛋白。它可以与肌动蛋白、肌球蛋白、原肌球蛋白和钙调素相互作用。

Calretinin is a calcium-binding protein which is abundant in auditory neurons. It belongs to the calbindin family. Calbindin 2 (calretinin), closely related to calbindin 1, is an intracellular calcium-binding protein belonging to the troponin C superfamily. Calbindin 1 is known to be involved in the vitamin-D-dependent calcium absorption through intestinal and renal epithelia, while the function of neuronal calbindin 1 and calbindin2 is poorly understood. The sequence of the calbindin 2 cDNA reveals an open reading frame of 271 codons coding for a protein of 31,520 Da, and shares 58% identical residues with human calbindin1.