MRC1 Recombinant Rabbit mAb (一抗) - WB,Flow-Cyt,ICC/IF | Bioss

bsm-52791R

重组兔单抗

MRC1 Recombinant Rabbit mAb

巨噬细胞甘露糖受体 (CD206)重组兔单抗

CD206; CLEC13D; CLEC13DL; MMR; MRC1L1; bA541I19.1; hMR; MR; MRC1_HUMAN; MRC1; C-type lectin domain family 13 member D; C-type lectin domain family 13 member D-like; Human mannose receptor (hMR); Macrophage mannose receptor 1-like protein 1; MRC1_MOUSE; mannose receptor C-type 1; mannose receptor, C type 1-like 1; mannose receptor, C type 1; macrophage mannose receptor

Rabbit

A synthesized peptide derived from human MRC1: 1400-1456/1456

IgG

Liquid

affinity purified by Protein A

Recombinant

5C9

166/140 kDa

165 kDa

1mg/ml

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

巨噬细胞甘露糖受体,主要存在于巨噬细胞膜表面的模式识别受体，能够特异性识别甘露糖、岩藻糖或N-乙酰葡糖胺，介导巨噬细胞吞噬抗原，启动免疫反应.

The recognition of complex carbohydrate structures on glycoproteins is an important part of several biological processes, including cell-cell recognition, serum glycoprotein turnover, and neutralization of pathogens. The protein encoded by this gene is a type I membrane receptor that mediates the endocytosis of glycoproteins by macrophages. The protein has been shown to bind high-mannose structures on the surface of potentially pathogenic viruses, bacteria, and fungi so that they can be neutralized by phagocytic engulfment. This gene is in close proximity to MRC1L1. The gene loci including this gene, MRC1L1, as well as LOC340843 and LOC340893, consist of two nearly identical, tandemly linked genomic regions, which are thought to be a part of a duplicated region. [provided by RefSeq].

MRC1

Macrophage mannose receptor 1

Endosome membrane; Single-pass type I membrane protein. Cell membrane; Single-pass type I membrane protein.

Contains 8 C-type lectin domains.
Contains 1 fibronectin type-II domain.
[SIMILARITY] Contains 1 ricin B-type lectin domain.

Mediates the endocytosis of glycoproteins by macrophages. Binds both sulfated and non-sulfated polysaccharide chains. Acts as phagocytic receptor for bacteria, fungi and other pathogens.