DRD1 Recombinant Rabbit mAb (一抗) - WB | Bioss

bsm-52920R

重组兔单抗

DRD1 Recombinant Rabbit mAb

多巴胺受体D1重组兔单抗

D1R; DADR; DRD1A; C030036C15Rik; Drd-1; Gpcr15; D1a; DRD1_HUMAN; DRD1; Dopamine D1 receptor; DRD1_MOUSE; DRD1_RAT; dopamine receptor D1

Rabbit

C-terminus human Dopamine Receptor D1

IgG

Liquid

affinity purified by Protein A

Recombinant

3C3

50 kDa

72 kDa

1mg/ml

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

多巴胺受体D1在运动协调方面起重要作用，该受体的缺失对黑质多巴胺能神经元的影响程度虽没临床帕金森病（PD）严重，但仍可加速多巴胺能神经元发生退行性改变.该蛋白目前主要用于神经退行性改变的研究。

This gene encodes the D1 subtype of the dopamine receptor. The D1 subtype is the most abundant dopamine receptor in the central nervous system. This G-protein coupled receptor stimulates adenylyl cyclase and activates cyclic AMP-dependent protein kinases. D1 receptors regulate neuronal growth and development, mediate some behavioral responses, and modulate dopamine receptor D2-mediated events. Alternate transcription initiation sites result in two transcript variants of this gene. [provided by RefSeq, Jul 2008]

DRD1

D(1A) dopamine receptor

Interacts with DNAJC14 via its C-terminus. Interacts with DRD1IP.

Cell membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein.

Detected in caudate, nucleus accumbens and in the olfactory tubercle.

Belongs to the G-protein coupled receptor 1 family.

Dopamine receptor whose activity is mediated by G proteins which activate adenylyl cyclase.