神经生长因子β重组兔单抗

bsm-52362R

重组兔单抗

NGF Recombinant Rabbit mAb

神经生长因子β重组兔单抗

Beta-NGF; HSAN5; NGFB; NGF_HUMAN; NGF; NGF_MOUSE; NGF_RAT;

Rabbit

A synthesized peptide derived from human beta NGF: 202-241

IgG

Liquid

affinity purified by Protein A

Recombinant

11G1

13/32 kDa

1mg/ml

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

神经生长因子-β(NGF-β)属于一种对神经元的生长、分化、延长存活期有促进作用的神经生长因子家族。此抗体识别分子量为29kDa 的NGF蛋白。
神经生长因子(Nerve Growth Factor,NGF)是最早被发现、兼有神经元营养和促突触生长双重生物学功能的一种细胞调节因子.它对中枢和周围神经元的发育、分化、生长、再生和功能特性的表达均具有重要的调控作用,可促进受损神经再生、免受继发性损害、减少细胞死亡、支持神经元存活等功能.

This gene is a member of the NGF-beta family and encodes a secreted protein which homodimerizes and is incorporated into a larger complex. This protein has nerve growth stimulating activity and the complex is involved in the regulation of growth and the differentiation of sympathetic and certain sensory neurons. Mutations in this gene have been associated with hereditary sensory and autonomic neuropathy, type 5 (HSAN5), and dysregulation of this gene's expression is associated with allergic rhinitis. [provided by RefSeq, Jul 2008]