CK820_G0013410; HCIN; HMNDYT2; LZT-Hs4; NET34; ZIP14; cig19; FAD-123; ZIP-14; fad123; CR201_G0005121; S39AE_HUMAN; SLC39A14; LIV-1 subfamily of ZIP zinc transporter 4 (LZT-Hs4); Solute carrier family 39 member 14; Zrt- and Irt-like protein 14 (ZIP-14); KIAA0062; S39AE_MOUSE; Factor for adipocyte differentiation 123 (FAD-123); S39AE_PONAB; solute carrier family 39 (metal ion transporter), member 14; solute carrier family 39 (zinc transporter), member 14; zinc transporter 14; ZRT/IRT-like protein 14; Metal cation symporter ZIP14
抗体来源
Rabbit
免疫原
KLH conjugated synthetic peptide derived from human SLC39A14: 51-150/492
亚型
IgG
性状
Liquid
纯化方法
affinity purified by Protein A
克隆类型
Polyclonal
理论分子量
51 kDa
浓度
1mg/ml
储存液
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Zinc is an essential cofactor for hundreds of enzymes. It is involved in protein, nucleic acid, carbohydrate, and lipid metabolism, as well as in the control of gene transcription, growth, development, and differentiation. SLC39A14 belongs to a subfamily of proteins that show structural characteristics of zinc transporters (Taylor and Nicholson, 2003 [PubMed 12659941]).[supplied by OMIM, Mar 2008]
产品应用
应用
已检合格种属
预测种属
推荐稀释比例
IHC-P
Human, Mouse, Rat
1:100-500
IHC-F
Human, Mouse, Rat
1:100-500
IF
Human, Mouse, Rat
1:100-500
ICC/IF
Human, Mouse, Rat
1:50 - 1:200
ELISA
Human, Mouse, Rat
1:1000-5000
交叉反应
交叉反应: Human, Mouse, Rat
相关产品
暂无相关产品
靶标
基因名
SLC39A14
蛋白名
Metal cation symporter ZIP14
亚基
Homotrimer.
亚细胞定位
Cell membrane. Cell projection > lamellipodium. Localized to the plasma membrane and also found colocalized with F-actin concentrated on lamellipodiae.
组织特异性
Ubiquitously expressed, with increased expression in liver, pancreas, fetal liver, thyroid gland, left and right ventricle, right atrium and fetal heart. Weakly expressed in spleen, thymus, and peripheral blood leukocytes.
相似性
Belongs to the ZIP transporter (TC 2.A.5) family.
功能
May be able to transport iron (By similarity). Acts as a zinc-influx transporter.