尾型同源盒转录因子2重组兔单抗

bsm-52348R

重组兔单抗、病理级抗体

CDX2 Recombinant Rabbit mAb

尾型同源盒转录因子2重组兔单抗

CDX-3; CDX2/AS; CDX3; Cdx-2; CDX2_HUMAN; CDX2; Caudal-type homeobox protein 2; CDX2_MOUSE;

Rabbit

A synthesized peptide derived from human CDX2: 11-76/313

IgG

Liquid

affinity purified by Protein A

Recombinant

3G7

34 kDa

1mg/ml

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

核转录因子抗体 CDX2表达主要用于消化系统肿瘤及癌前病变的研究。用于与肿瘤的增值、分化、大小、临床分期及分化程度等关系方面的研究。CDX2是一种肠特异的转录因子，CDX2能够调节肠上皮细胞的增殖和分化，定位于肠上皮的绒毛和隐窝表面。据报道95%以上的浸润性结/直肠癌中均可检出CDX2阳性表达，也可在胃癌和卵巢黏液性腺癌中表达。

This gene is a member of the caudal-related homeobox transcription factor gene family. The encoded protein is a major regulator of intestine-specific genes involved in cell growth an differentiation. This protein also plays a role in early embryonic development of the intestinal tract. Aberrant expression of this gene is associated with intestinal inflammation and tumorigenesis. [provided by RefSeq, Jan 2012]