神经元核抗原重组兔单抗
Rrmab®兔单抗
货号：bsm-52268R
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概述
产品编号
bsm-52268R
产品类型
重组兔单抗、mIHC精品抗体
英文名称
NeuN Recombinant Rabbit mAb
中文名称
神经元核抗原重组兔单抗
英文别名
FOX-3; FOX3; HRNBP3; NEUN; Neuna60; RGD1560070; RFOX3_HUMAN; RBFOX3; Fox-1 homolog C; Neuronal nuclei antigen (NeuN antigen); RFOX3_MOUSE; Hexaribonucleotide-binding protein 3 (Fox-3); D11Bwg0517e;
抗体来源
Rabbit
免疫原
KLH conjugated synthetic peptide derived from human NeuN
亚型
IgG
性状
Liquid
纯化方法
affinity purified by Protein A
克隆类型
Recombinant
克隆号
12C3
理论分子量
34 kDa
浓度
1mg/ml
储存液
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
研究领域
Epigenetics and Nuclear Signaling > Transcription > Domain Families > Forkhead Box > Other FOXes
Epigenetics and Nuclear Signaling > Transcription > Transcription Factors
Neuroscience > Cell Type Marker > Neuron marker > Soma marker
Signal Transduction > Antibodies > neun
Tags & Cell Markers > Cell Type Markers > Neuroscience Markers > Neuronal
SWISS
Gene ID
保存条件
Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
数据库链接
产品介绍
神经生物学相关蛋白（Neurobiology）
背景资料
This gene encodes a member of the RNA-binding FOX protein family which is involved in the regulation of alternative splicing of pre-mRNA. The protein has an N-terminal proline-rich region, an RNA recognition motif (RRM) domain, and a C-terminal alanine-rich region. This gene produces the neuronal nuclei (NeuN) antigen that has been widely used as a marker for post-mitotic neurons. This gene has its highest expression in the central nervous system and plays a prominent role in neural tissue development and regulation of adult brain function. Mutations in this gene have been associated with numerous neurological disorders. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, May 2017]
产品应用
| 应用 | 已检合格种属 | 预测种属 | 推荐稀释比例 |
|---|---|---|---|
| WB | Mouse, Rat | Human | 1:500-2000 |
| IHC-P | Human, Mouse, Rat | 1:100-500 | |
| IHC-F | Human, Mouse, Rat | 1:100-500 | |
| IF | Human, Mouse, Rat | 1:100-500 | |
| Flow-Cyt | Human | Mouse, Rat | 1:50-100 |
交叉反应
交叉反应: Human, Mouse, Rat
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靶标
基因名
RBFOX3
蛋白名
RNA binding protein fox-1 homolog 3
亚细胞定位
Nucleus. Cytoplasm.
组织特异性
Expressed in activated, but not resting, CD4+ T-cells and activated monocytes.
相似性
Contains 1 RRM (RNA recognition motif) domain.
功能
RNA-binding protein that regulates alternative splicing events.
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