VDAC Rabbit pAb, Loading Control (一抗) | Bioss

bs-1461R

内参抗体、宠物抗体、农牧业/家禽抗体、离子通道抗体

VDAC Rabbit pAb, Loading Control

等电压依赖性阴离子通道（内参）抗体

PORIN; VDAC-1; Vdac5; mVDAC1; mVDAC5; fa13f11; wu:fa13f11; zgc:85830; voltage dependent anion channel 1

Rabbit

KLH conjugated synthetic peptide derived from human VDAC: 85-190/283

IgG

Liquid

affinity purified by Protein A

Polyclonal

32 kDa

25 kDa

1mg/ml

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

电压依赖性阴离子通道VDAC是存在于线粒体外膜上的31kDa蛋白,能在膜上形成亲水性通道,调控阴离子、阳离子、ATP以及其他代谢物进出线粒体,在调节细胞代谢、维持胞内钙稳态,调节细胞凋亡和坏死等过程中发挥重要功能。

Voltage dependent anion selective channel protein 1 (VDAC/Porin) belongs to the eukaryotic mitochondrial porin family and forms a channel through the mitochondrial outer membrane and also the plasma membrane. The channel allows diffusion of small hydrophilic molecules; it adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV. The open state has a weak anion selectivity whereas the closed state is cation selective. VDAC/Porin expression is observed in the heart,liver and skeletal muscle.