phospho-HNF4 (Ser313) Rabbit pAb (一抗) | Bioss

bs-4001R

磷酸化抗体、乙酰化抗体、农牧业/家禽抗体

phospho-HNF4 (Ser313) Rabbit pAb

磷酸化肝细胞核因子4α抗体

HNF4A | HNF4 (phospho-S313); p-HNF4; phospho-HNF4; p-HNF4A; HNF4A | HNF4 (phospho-Ser313); FRTS4; HNF4; HNF4a7; HNF4a8; HNF4a9; HNF4alpha; MODY; MODY1; NR2A1; NR2A21; TCF; TCF-14; TCF14; HNF-4; HNF4A_HUMAN; HNF4A; HNF-4-alpha; Nuclear receptor subfamily 2 group A member 1; Transcription factor 14 (TCF-14); Transcription factor HNF-4; HNF4A_MOUSE; HNF4A_RAT;

Rabbit

KLH conjugated Synthesised phosphopeptide derived from human HNF4 alpha around the phosphorylation site of Ser313: LR(p-S)QV

IgG

Liquid

affinity purified by Protein A

Polyclonal

52 kDa

50 kDa

1mg/ml

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

肝细胞核因子α(HNF4 α)是一类异质的保守转录因子,参与调节肝脏内糖代谢、脂代谢相关基因的表达.HNF在胰岛中也有表达.HNF4-α目前用于2型糖尿病的研究也很多。

The protein encoded by the HNF4 gene is a nuclear transcription factor which binds DNA as a homodimer. The encoded protein controls the expression of several genes, including hepatocyte nuclear factor 1 alpha, a transcription factor which regulates the expression of several hepatic genes. This gene may play a role in development of the liver, kidney, and intestines. Mutations in this gene have been associated with monogenic autosomal dominant non insulin dependent diabetes mellitus type I. At least three different transcript variants encoding three different isoforms have been found for this gene.