PDK1/Mitochondrial Pyruvate dehydrogenase kinase 1 Rabbit pAb (一抗) | Bioss

2026-05-01~2026-06-30,AB2605
PDK1/Mitochondrial Pyruvate dehydrogenase kinase 1 Rabbit pAb (一抗) | Bioss
货号:bs-3788R
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概述

产品编号
bs-3788R
产品类型
宠物抗体、农牧业/家禽抗体
英文名称
PDK1/Mitochondrial Pyruvate dehydrogenase kinase 1 Rabbit pAb
中文名称
丙酮酸脱氢酶激酶1抗体
英文别名
B830012B01; D530020C15Rik; PDK1_HUMAN; PDK1; Pyruvate dehydrogenase kinase isoform 1 (PDH kinase 1); 2.7.11.2; PDHK1; PDK1_MOUSE; PDK1_RAT; PDK p48; Pdh; pyruvate dehydrogenase kinase 1; pyruvate dehydrogenase kinase, isoenzyme 1; pyruvate dehydrogenase kinase, isozyme 1
抗体来源
Rabbit
免疫原
KLH conjugated synthetic peptide derived from human PDK1: 51-150/436
亚型
IgG
性状
Liquid
纯化方法
affinity purified by Protein A
克隆类型
Polyclonal
理论分子量
45 kDa
检测分子量
50 kDa
浓度
1mg/ml
储存液
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
SWISS
Gene ID
保存条件
Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
背景资料
Pyruvate dehydrogenase (PDH) is a mitochondrial multienzyme complex that catalyzes the oxidative decarboxylation of pyruvate and is one of the major enzymes responsible for the regulation of homeostasis of carbohydrate fuels in mammals. The enzymatic activity is regulated by a phosphorylation/dephosphorylation cycle. Phosphorylation of PDH by a specific pyruvate dehydrogenase kinase (PDK) results in inactivation. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jun 2013]
丙酮酸脱氢酶激酶1抗体-bs-3788R丙酮酸脱氢酶激酶1抗体-bs-3788R丙酮酸脱氢酶激酶1抗体-bs-3788R

产品应用

应用已检合格种属预测种属推荐稀释比例
WBMouse, RatHuman, Rabbit, Pig, Cow, Chicken, Dog, Horse1:500-2000
IHC-PMouseHuman, Rat, Rabbit, Pig, Cow, Chicken, Dog, Horse1:100-500
IHC-FMouseHuman, Rat, Rabbit, Pig, Cow, Chicken, Dog, Horse1:100-500
IFMouseHuman, Rat, Rabbit, Pig, Cow, Chicken, Dog, Horse1:100-500
Flow-CytHumanMouse, Rat, Rabbit, Pig, Cow, Chicken, Dog, Horse1ug/Test

交叉反应

交叉反应: Human, Mouse, Rat (predicted: Rabbit, Pig, Cow, Chicken, Dog, Horse)

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暂无相关产品

靶标

基因名
PDK1
蛋白名
[Pyruvate dehydrogenase(acetyl-transferring)] kinase isozyme 1, mitochondrial
亚细胞定位
Mitochondrion matrix.
组织特异性
Expressed predominantly in the heart.
相似性
Belongs to the PDK/BCKDK protein kinase family.
Contains 1 histidine kinase domain.
功能
Inhibits the mitochondrial pyruvate dehydrogenase complex by phosphorylation of the E1 alpha subunit, thus contributing to the regulation of glucose metabolism.

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具体参考文献:bs-3788R 被引用于3文献中

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