英文名称
ATP1B2 | AMOG Rabbit pAb, Loading Control
英文别名
AMOG; AT1B2_HUMAN; ATP1B2; Adhesion molecule in glia (AMOG); Sodium/potassium-dependent ATPase subunit beta-2; ATPase Na+/K+ transporting subunit beta 2; ATPase, Na+/K+ transporting, beta 2 polypeptide; sodium/potassium-transporting ATPase subunit beta-2; sodium pump subunit beta-2; sodium-potassium ATPase subunit beta 2 (non-catalytic)
免疫原
KLH conjugated synthetic peptide derived from human ATP1b2: 201-290/290
纯化方法
affinity purified by Protein A
储存液
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存条件
Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍
通道蛋白(Channel Protein)
钠钾ATP酶是位于细胞膜上的一种糖蛋白,与ATP 的分解和细胞内外钠、钾离子的转运密切相关,哺乳动物各种组织细胞的钠钾ATP 酶的免疫学特性基本相同。
背景资料
The protein encoded by this gene belongs to the family of Na+/K+ and H+/K+ ATPases beta chain proteins, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane. The glycoprotein subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes a beta 2 subunit. [provided by RefSeq, Jul 2008]
蛋白名
Sodium/potassium-transporting ATPase subunit beta-2
亚基
Composed of three subunits: alpha (catalytic), beta and gamma.
亚细胞定位
Membrane; Single-pass type II membrane protein.
相似性
Belongs to the X(+)/potassium ATPases subunit beta family.
功能
This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The exact function of the beta-2 subunit is not known.