肥大细胞类胰蛋白酶重组兔单抗

bsm-52533R

重组兔单抗

Mast Cell Tryptase Recombinant Rabbit mAb

肥大细胞类胰蛋白酶重组兔单抗

TPS1; TPS2; TPSB1; TPSB2; Tryptase-2; MMCP-7; Mcp-7; Mcp7; Mcpt7; rMCP-7; TRYB1_HUMAN; TPSAB1; Tryptase-1; Tryptase I; Tryptase alpha-1; 3.4.21.59; TRYB1_MOUSE; Mast cell protease 7 (mMCP-7); Tryptase alpha/beta-1; TRYB1_RAT; Mast cell protease 7 (rMCP-7); Tryptase, skin; TRYB2_HUMAN; Tryptase II;

Rabbit

A synthesized peptide derived from human Tryptase 1: 10-275/275

IgG

Liquid

affinity purified by Protein A

Recombinant

3G3

23 kDa

1mg/ml

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

Tryptases comprise a family of trypsin-like serine proteases, the peptidase family S1. Tryptases are enzymatically active only as heparin-stabilized tetramers, and they are resistant to all known endogenous proteinase inhibitors. Several tryptase genes are clustered on chromosome 16p13.3. These genes are characterized by several distinct features. They have a highly conserved 3' UTR and contain tandem repeat sequences at the 5' flank and 3' UTR which are thought to play a role in regulation of the mRNA stability. Although this gene may be an exception, most of the tryptase genes have an intron immediately upstream of the initiator Met codon, which separates the site of transcription initiation from protein coding sequence. This feature is characteristic of tryptases but is unusual in other genes. Tryptases have been implicated as mediators in the pathogenesis of asthma and other allergic and inflammatory disorders. This gene was once considered to be a pseudogene, although it is now believed to be a functional gene that encodes a protein. [provided by RefSeq, Jul 2008]