肿瘤坏死因子受体2重组兔单抗

bsm-52938R

重组兔单抗

TNFR2 Recombinant Rabbit mAb

肿瘤坏死因子受体2重组兔单抗

CD120b; TBPII; TNF-R-II; TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80; p75; p75TNFR; TNF-R2; TNF-alphaR2; TNFRII; TNFalpha-R2; Tnfr-1; TNR1B_HUMAN; TNFRSF1B; Tumor necrosis factor receptor 2 (TNF-R2); Tumor necrosis factor receptor type II (TNF-RII | TNFR-II); p80 TNF-alpha receptor; TNR1B_MOUSE; Tnfr-2; TNR1B_RAT;

Rabbit

A synthesized peptide derived from human TNFRSF1B: 415-461/461

IgG

Liquid

affinity purified by Protein A

Recombinant

7D3

46 kDa

1mg/ml

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein and TNF-receptor 1 form a heterocomplex that mediates the recruitment of two anti-apoptotic proteins, c-IAP1 and c-IAP2, which possess E3 ubiquitin ligase activity. The function of IAPs in TNF-receptor signalling is unknown, however, c-IAP1 is thought to potentiate TNF-induced apoptosis by the ubiquitination and degradation of TNF-receptor-associated factor 2, which mediates anti-apoptotic signals. Knockout studies in mice also suggest a role of this protein in protecting neurons from apoptosis by stimulating antioxidative pathways. [provided by RefSeq, Jul 2008]