ID; bHLHb24; D2Wsu140e; Idb1; ID125A; ID1_HUMAN; ID1; Class B basic helix-loop-helix protein 24 (bHLHb24); Inhibitor of DNA binding 1; Inhibitor of differentiation 1; ID1_MOUSE; Id-1; ID1_RAT;
抗体来源
Rabbit
免疫原
Recombinant human ID1 protein
亚型
IgG
性状
Liquid
纯化方法
affinity purified by Protein A
克隆类型
Recombinant
克隆号
5F1
理论分子量
16 kDa
浓度
1mg/ml
储存液
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4℃.
注意事项
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
ID proteins contain a helix-loop-helix (HLH) motif and regulate tissue-specific transcription within several cell lineages. They do not bind DNA directly, but inhibit lineage commitment by binding basic helix-loop-helix (bHLH) transcription factors through their HLH motif. ID proteins contribute to cell growth, senescence, differentiation and angiogenesis. Id1 mRNA is highly expressed in heart, lung and kidney and has lower expression in brain and liver. Two transcript variants encoding different isoforms have been found for this gene.
产品应用
应用
已检合格种属
预测种属
推荐稀释比例
IHC-P
Human
1:50-200
IHC-F
Human
1:50-200
IF
Human
1:50-200
Flow-Cyt
Human
1:50-100
ICC/IF
Human
1:50-200
交叉反应
交叉反应: Human
相关产品
暂无相关产品
靶标
基因名
ID1
蛋白名
DNA-binding protein inhibitor ID-1
亚基
Heterodimer with other HLH proteins. Interacts with COPS5.
亚细胞定位
Cytoplasm. Nucleus.
相似性
Contains 1 bHLH (basic helix-loop-helix) domain.
功能
ID (inhibitor of DNA binding) HLH proteins lack a basic DNA-binding domain but are able to form heterodimers with other HLH proteins, thereby inhibiting DNA binding.