phospho-MARCKS (Ser152 + Ser156) Rabbit pAb (一抗) | Bioss

2026-03-02~2026-04-30,KXJ26032026-03-02~2026-04-30,促销赠品
phospho-MARCKS (Ser152 + Ser156) Rabbit pAb (一抗) | Bioss
货号:bs-3263R
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概述

产品编号
bs-3263R
产品类型
磷酸化抗体、宠物抗体、农牧业/家禽抗体
英文名称
phospho-MARCKS (Ser152 + Ser156) Rabbit pAb
中文名称
磷酸化丙氨酸蛋白激酶C底物Marcks抗体
英文别名
MARCKS (phospho-S152/S156); p-MARCKS; phospho-MARCKS; MARCKS (phospho-Ser152/Ser156); 80K-L; MACS; PKCSL; PRKCSL; KINC; MARCS_HUMAN; MARCKS; Protein kinase C substrate, 80 kDa protein, light chain (80K-L protein | PKCSL); MARCS_MOUSE; MARCS_RAT; Protein kinase C substrate 80 kDa protein;
抗体来源
Rabbit
免疫原
KLH conjugated synthesised phosphopeptide derived from rat MARCKS around the phosphorylation site of Ser152/156 or Ser159/163(human) : RF(p-S)FKK(p-S)FK
亚型
IgG
性状
Liquid
纯化方法
affinity purified by Protein A
克隆类型
Polyclonal
理论分子量
30 kDa
检测分子量
30 kDa
浓度
1mg/ml
储存液
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
SWISS
Gene ID
保存条件
Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍
MARCKS是一种分子量为32kDa的膜内蛋白,在组织中广泛表达,但主要高表达在脑内的轴突、小直径的树突和树突棘.
背景资料
MARCKS, (Myristoylated Alanine-Rich C Kinase Substrate), is a member of a family of calmodulin binding proteins and is a major substrate for phosphorylation by protein kinase C (PKC). The phosphorylation of Ser152/156 can be used as a measure of PKC activation. Phosphorylation of Ser152/156 modulates the binding of MARCKS to calmodulin.
磷酸化丙氨酸蛋白激酶C底物Marcks抗体-bs-3263R磷酸化丙氨酸蛋白激酶C底物Marcks抗体-bs-3263R磷酸化丙氨酸蛋白激酶C底物Marcks抗体-bs-3263R

产品应用

应用已检合格种属预测种属推荐稀释比例
WBMouseHuman, Rat, Rabbit, Cow, Chicken, Dog1:500-2000
IHC-PRatHuman, Mouse, Rabbit, Cow, Chicken, Dog1:100-500
IHC-FRatHuman, Mouse, Rabbit, Cow, Chicken, Dog1:100-500
IFRatHuman, Mouse, Rabbit, Cow, Chicken, Dog1:100-500

交叉反应

交叉反应: Mouse, Rat (predicted: Human, Rabbit, Cow, Chicken, Dog)

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靶标

基因名
MARCKS
蛋白名
Myristoylated alanine-rich C-kinase substrate
亚细胞定位
Cytoplasm, cytoskeleton (Probable). Membrane; Lipid-anchor.
组织特异性
Highest levels found in spleen and brain. Intermediate levels seen in thymus, ovary, lung and heart. Very low levels seen in kidney, skeletal muscle and liver.
翻译后修饰
Phosphorylation by PKC displaces MARCKS from the membrane. It also inhibits the F-actin cross-linking activity.
相似性
Belongs to the MARCKS family.
功能
MARCKS is the most prominent cellular substrate for protein kinase C. This protein binds calmodulin, actin, and synapsin. MARCKS is a filamentous (F) actin cross-linking protein.

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