VCAM1 Rabbit pAb (一抗) - WB | Bioss

2026-05-01~2026-06-30,AB2605
VCAM1 Rabbit pAb (一抗) - WB | Bioss
货号:bs-0396R
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概述

产品编号
bs-0396R
英文名称
VCAM1 Rabbit pAb
中文名称
血管内皮细胞粘附分子(CD106)抗体
英文别名
CD106; INCAM-100; VCAM1_HUMAN; VCAM1; V-CAM 1; VCAM-1; vascular cell adhesion molecule 1
抗体来源
Rabbit
免疫原
Recombinant Mouse VCAM 1 protein <Extracellular>
亚型
IgG
性状
Liquid
纯化方法
affinity purified by Protein A
克隆类型
Polyclonal
理论分子量
81 kDa
检测分子量
100 kDa
浓度
1mg/ml
储存液
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存条件
Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍
VCAM 1(CD106)是一种膜相关蛋白,分布于血管内皮及其周围的淋巴细胞、单核细胞、嗜酸性粒细胞和中性粒细胞。Anti-VCAM-1主要用于各种组织中血管内皮的检测。
背景资料
VCAM1 is important in cell-cell recognition. Appears to function in leukocyte-endothelial cell adhesion. Interacts with the integrins alpha4 beta1 (beta 1 integrin VLA4) and alpha4 beta7 on leukocytes, and mediates both adhesion and signal transduction. The VCAM1/VLA4 interaction may play a pathophysiologic role both in immune responses and in leukocyte emigration to sites of inflammation. VCAM1 is also expressed by several non endothelial cell types including some macrophages, follicular dendritic cells and bone marrow, stromal cells.
血管内皮细胞粘附分子(CD106)抗体-bs-0396R

产品应用

应用已检合格种属预测种属推荐稀释比例
WBMouse1:500-2000

交叉反应

交叉反应: Mouse

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靶标

基因名
VCAM1
蛋白名
Vascular cell adhesion protein 1
亚基
Binds to ECMV-D capsid proteins and acts as a receptor for this virus.
亚细胞定位
Isoform 1: Cell membrane; Single-pass type I membrane protein. Isoform 2: Cell membrane; Lipid-anchor, GPI-anchor.
组织特异性
Expressed on inflamed vascular endothelium, as well as on macrophage-like and dendritic cell types in both normal and inflamed tissue. Expressed in the bone marrow.
相似性
Contains 7 Ig-like C2-type (immunoglobulin-like) domains.
功能
Important in cell-cell recognition. Appears to function in leukocyte-endothelial cell adhesion. Interacts with the beta-1 integrin VLA4 on leukocytes, and mediates both adhesion and signal transduction. The VCAM1/VLA4 interaction may play a pathophysiologic role both in immune responses and in leukocyte emigration to sites of inflammation.

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