DNase II Rabbit pAb (一抗) - WB | Bioss
货号：bs-7652R
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概述
产品编号
bs-7652R
产品类型
宠物抗体、农牧业/家禽抗体
英文名称
DNase II Rabbit pAb
中文名称
脱氧核糖核酸酶2抗体
英文别名
AIPCS; DNASE2A; DNL; DNL2; DNS2A_HUMAN; DNASE2; Acid DNase; Deoxyribonuclease II alpha (DNase II alpha); Lysosomal DNase II; R31240_2; 3.1.22.1;
抗体来源
Rabbit
免疫原
KLH conjugated synthetic peptide derived from human DNase II: 25-90/360
亚型
IgG
性状
Liquid
纯化方法
affinity purified by Protein A
克隆类型
Polyclonal
理论分子量
38 kDa
检测分子量
45 kDa
浓度
1mg/ml
储存液
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
研究领域
SWISS
Gene ID
保存条件
Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
背景资料
Hydrolyzes DNA under acidic conditions with a preference for double-stranded DNA. Plays a major role in the degradation of nuclear DNA in cellular apoptosis during development. Necessary for proper fetal development and for definitive erythropoiesis in fetal liver, where it degrades nuclear DNA expelled from erythroid precursor cells.
产品应用
| 应用 | 已检合格种属 | 预测种属 | 推荐稀释比例 |
|---|---|---|---|
| WB | Human, Mouse, Rat | Rabbit, Pig, Sheep, Cow, Dog, Horse | 1:500-2000 |
交叉反应
交叉反应: Human, Mouse, Rat (predicted: Rabbit, Pig, Sheep, Cow, Dog, Horse)
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靶标
基因名
DNASE2
蛋白名
DNASE1
亚细胞定位
Lysosome.
翻译后修饰
Glycosylated. Mutations that eliminate N-glycosylation sites reduce activity, but enzymatic deglycosylation has no effect.
相似性
Belongs to the DNase II family.
功能
Hydrolyzes DNA under acidic conditions with a preference for double-stranded DNA. Plays a major role in the degradation of nuclear DNA in cellular apoptosis during development. Necessary for proper fetal development and for definitive erythropoiesis in fetal liver, where it degrades nuclear DNA expelled from erythroid precursor cells.
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