TNFSF13B Rabbit pAb (一抗) | Bioss
货号：bs-2431R
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概述
产品编号
bs-2431R
产品类型
农牧业/家禽抗体
英文名称
TNFSF13B Rabbit pAb
中文名称
肿瘤坏死因子配体超家族成员13B抗体
英文别名
BAFF; BLYS; CD257; DTL; TALL-1; TALL1; THANK; TNFSF20; TNLG7A; ZTNF4; D8Ertd387e; TN13B_HUMAN; TNFSF13B; B lymphocyte stimulator (BLyS); B-cell-activating factor; Dendritic cell-derived TNF-like molecule; TNF- and APOL-related leukocyte expressed ligand 1 (TALL-1); TN13B_MOUSE;
抗体来源
Rabbit
免疫原
KLH conjugated synthetic peptide derived from mouse TNFSF13B: 221-309/309
亚型
IgG
性状
Liquid
纯化方法
affinity purified by Protein A
克隆类型
Polyclonal
理论分子量
34 kDa
检测分子量
52 kDa
浓度
1mg/ml
储存液
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
研究领域
SWISS
Gene ID
保存条件
Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
数据库链接
背景资料
The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptors TNFRSF13B/TACI, TNFRSF17/BCMA, and TNFRSF13C/BAFFR. This cytokine is expressed in B cell lineage cells, and acts as a potent B cell activator. It has been also shown to play an important role in the proliferation and differentiation of B cells. [provided by RefSeq].
产品应用
| 应用 | 已检合格种属 | 预测种属 | 推荐稀释比例 |
|---|---|---|---|
| WB | Human | Mouse, Rat, Rabbit, Pig, Cow | 1:500-2000 |
| Flow-Cyt | Human | Mouse, Rat, Rabbit, Pig, Cow | 3μg/Test |
| ELISA | Human | Mouse, Rat, Rabbit, Pig, Cow | 1:5000-10000 |
交叉反应
交叉反应: Human (predicted: Mouse, Rat, Rabbit, Pig, Cow)
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靶标
基因名
TNFSF13B
蛋白名
Tumor necrosis factor ligand superfamily member 13B
亚基
Belongs to the tumor necrosis factor family.
亚细胞定位
Secreted and Cell membrane.
组织特异性
Abundantly expressed in peripheral blood Leukocytes and is specifically expressed in monocytes and macrophages. Also found in the spleen, lymph node, bone marrow, T-cells and dendritic cells. A lower expression seen in placenta, heart, lung, fetal liver, thymus, and pancreas.
翻译后修饰
The soluble form derives from the membrane form by proteolytic processing.
Isoform 2 is not efficiently shed from the membrane unlike isoform 1.
Isoform 2 is not efficiently shed from the membrane unlike isoform 1.
相似性
Belongs to the tumor necrosis factor family.
功能
Cytokine that binds to TNFRSF13B/TACI and TNFRSF17/BCMA. TNFSF13/APRIL binds to the same 2 receptors. Together, they form a 2 ligands -2 receptors pathway involved in the stimulation of B-and T-cell function and the regulation of humoral immunity. A third B-cell specific BAFF-receptor (BAFFR/BR3) promotes the survival of mature B-cells and the B-cell response.
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