The Annexins are a family of structurally similar proteins. Annexins bind to phospholipids and may be involved in regulation of membrane transport, membrane channel activity, and interaction of the cell membrane with the extracellular matrix. Annexin A4 (ANXA4) belongs to the annexin family of calcium dependent phospholipid binding proteins. Although their functions are still not clearly defined, several members of the annexin family have been implicated in membrane related events along exocytotic and endocytotic pathways. ANXA4 has 45 to 59% identity with other members of its family and shares a similar size and exon intron organization. Isolated from human placenta, ANXA4 encodes a protein that has possible interactions with ATP, and has in vitro anticoagulant activity and also inhibits phospholipase A2 activity. ANXA4 is almost exclusively expressed in epithelial cells.
产品应用
应用
已检合格种属
预测种属
推荐稀释比例
WB
Human
Mouse, Rat, Rabbit, Pig, Cow, Dog
1:500-2000
交叉反应
交叉反应: Human (predicted: Mouse, Rat, Rabbit, Pig, Cow, Dog)
相关产品
暂无相关产品
靶标
基因名
ANXA4
蛋白名
Annexin A4
相似性
Belongs to the annexin family.
Contains 4 annexin repeats.
功能
Calcium/phospholipid-binding protein which promotes membrane fusion and is involved in exocytosis.