NPY2R Rabbit pAb (一抗) | Bioss

2026-05-01~2026-06-30,AB2605
NPY2R Rabbit pAb (一抗) | Bioss
货号:bs-0937R
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概述

产品编号
bs-0937R
产品类型
农牧业/家禽抗体
英文名称
NPY2R Rabbit pAb
中文名称
神经肽Y受体2抗体
英文别名
NPY2-R; NPY2R_HUMAN; NPY2R; NPY-Y2 receptor (Y2 receptor); NPY2R_MOUSE; neuropeptide Y receptor Y2
抗体来源
Rabbit
免疫原
KLH conjugated synthetic peptide derived from human NPY2R: 301-381/381
亚型
IgG
性状
Liquid
纯化方法
affinity purified by Protein A
克隆类型
Polyclonal
理论分子量
43 kDa
检测分子量
43 kDa
浓度
1mg/ml
储存液
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
SWISS
Gene ID
保存条件
Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
背景资料
Neuropeptide Y (NPY), a peptide widely expressed in the brain, acts through the protein G-coupled receptors Y1, Y2 and Y5. This peptide modulates many important functions such as the control of energy balance and anxiety. Its involvement in brain development has been less investigated.
Neuropeptide Y (NPY) receptors are members of a G protein coupled receptor superfamily and they mediate a variety of physiological responses including feeding and vasoconstriction. The endogenous ligands of NPY receptors are a family of structurally related peptides, including NPY, peptide YY (PYY), and pancreatic polypeptide (PP). Increased activity of NPY and its receptors, Y1R, Y2R, and Y5R has been found in the brain in many forms of experimental obesity. Furthermore, several association studies have supported the association between NPY2R and obesity.
神经肽Y受体2抗体-bs-0937R神经肽Y受体2抗体-bs-0937R神经肽Y受体2抗体-bs-0937R

产品应用

应用已检合格种属预测种属推荐稀释比例
WBHuman, Mouse, RatPig1:500-2000
IHC-PRatHuman, Mouse, Pig1:100-500
IHC-FRatHuman, Mouse, Pig1:100-500
IFRatHuman, Mouse, Pig1:100-500

交叉反应

交叉反应: Human, Mouse, Rat (predicted: Pig)

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靶标

基因名
NPY2R
蛋白名
Neuropeptide Y receptor type 2
亚细胞定位
Cell membrane.
组织特异性
High levels in amygdala, corpus callosum, hippocampus and subthalamic nucleus. Also detectable in caudate nucleus, hypothalamus and substantia nigra.
相似性
Belongs to the G-protein coupled receptor 1 family.
功能
Receptor for neuropeptide Y and peptide YY. The rank order of affinity of this receptor for pancreatic polypeptides is PYY > NPY > PYY (3-36) > NPY (2-36) > [Ile-31, Gln-34] PP > [Leu-31, Pro-34] NPY > PP, [Pro-34] PYY and NPY free acid.

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具体参考文献:bs-0937R 被引用于3文献中

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