TSHB Recombinant Rabbit mAb (一抗) - WB,IHC-P,IHC-F,IF | Bioss

Cancer > Cancer Metabolism > Metabolic signaling pathway > Hormone biosynthesis

Metabolism > Pathways and Processes > Endocrine metabolism > Hormone biosynthesis

Neuroscience > Endocrine system > Thyroid axis

Signal Transduction > Growth Factors/Hormones > Hormones

Entrez Gene : 7252 Human

SwissProt : P01222 Human

TSHB（甲状腺刺激激素亚基Beta）是一种蛋白质编码基因。 与TSHB相关的疾病包括甲状腺功能减退，先天性，非甲状腺功能减退4和中枢性先天性甲状腺功能减退。其相关途径包括通过GPCR进行信号传递和肽激素代谢。与该基因相关的基因本体论（GO）注释包括激素活性。该基因的重要旁系同源物是FSHB。

The four human glycoprotein hormones chorionic gonadotropin (CG), luteinizing hormone (LH), follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH) are dimers consisting of alpha and beta subunits that are associated noncovalently. The alpha subunits of these hormones are identical, however, their beta chains are unique and confer biological specificity. Thyroid stimulating hormone functions in the control of thyroid structure and metabolism. The protein encoded by this gene is the beta subunit of thyroid stimulating hormone. Mutations in this gene are associated with congenital central and secondary hypothyroidism and Hashimoto's thyroiditis. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, May 2013]