促黄体素β亚单位重组兔单抗

Rrmab®兔单抗
2026-01-04~2026-02-28,RR26012026-01-04~2026-02-28,TR
促黄体素β亚单位重组兔单抗
货号:bsm-60576R
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概述

产品编号
bsm-60576R
产品类型
重组兔单抗、mIHC精品抗体
英文名称
LHB Recombinant Rabbit mAb
中文名称
促黄体素β亚单位重组兔单抗
英文别名
CGB4; HH23; LSH-B; LSH-beta; Gm29035; LH; LH-B; LSHB_HUMAN; LHB; Lutropin beta chain; Luteinizing hormone subunit beta (LH-B | LSH-B | LSH-beta); LSHB_MOUSE; LSHB_RAT;
抗体来源
Rabbit
亚型
IgG
性状
Liquid
纯化方法
affinity purified by Protein A
克隆类型
Recombinant
克隆号
E5C7
理论分子量
16 kDa
浓度
1mg/ml
储存液
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存条件
Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍
LH和FSH都是垂体前叶产生的,由两条多肽链(即а和β亚单位)经非共价键结合的糖蛋白。LH和FSH都是呈脉冲式分泌,故有较明显的日内和日间变异。
女性月经中期的LH高峰促成排卵,男性LH主要刺激Legdig细胞产生睾丸酮,又协同FSH促进精子成熟。与FSH同时测定,是研究和判断下丘脑 — 垂体 — 性腺轴功能的常规检查方法。LH的测定在预测排卵时间上具有特殊重要意义,它还可用于绝经期检查,不孕症诊断和内分泌治疗的监测等。
背景资料
Luteinizing Hormone is a member of the glycoprotein hormone family. Glycoprotein hormones are heterodimers consisting of a common alpha subunit and an unique beta subunit which confers biological specificity. LH is expressed in the pituitary gland and promotes spermatogenesis and ovulation by stimulating the testes and ovaries to synthesize steroids. Mutations in the Luteinizing Hormone (LHB) gene are associated with hypogonadism which is characterized by infertility and pseudohermaphroditism.
促黄体素β亚单位重组兔单抗促黄体素β亚单位重组兔单抗

产品应用

应用已检合格种属预测种属推荐稀释比例
WBRatHuman, Mouse1:500-2000
IHC-PHumanMouse, Rat1:100-500
IHC-FHumanMouse, Rat1:100-500
IFHumanMouse, Rat1:100-500

交叉反应

交叉反应: Human, Rat (predicted: Mouse)

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靶标

基因名
LHB
蛋白名
Lutropin subunit beta
亚基
Heterodimer of a common alpha chain and a unique beta chain which confers biological specificity to thyrotropin, lutropin, follitropin and gonadotropin.
亚细胞定位
Secreted.
组织特异性
Pituitary gland.
疾病
Hypogonadism LHB-related (HGON-LHB) [MIM:152780]: Characterized by infertility and pseudohermaphroditism. Note=The disease is caused by mutations affecting the gene represented in this entry.
相似性
Belongs to the glycoprotein hormones subunit beta family.
功能
Promotes spermatogenesis and ovulation by stimulating the testes and ovaries to synthesize steroids.

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