胚胎干细胞关键蛋白重组兔单抗

bsm-63076R

重组兔单抗

Oct4 Recombinant Rabbit mAb

胚胎干细胞关键蛋白重组兔单抗

OCT3; OCT4; OCT4Borf1; OTF-3; OTF3; OTF4; Oct-3; Oct-4; Oct3/4; NF-A3; Oct-3/4; Otf-4; Otf3-rs7; Otf3g; PO5F1_HUMAN; POU5F1; Octamer-binding protein 3 (Oct-3); Octamer-binding protein 4 (Oct-4); Octamer-binding transcription factor 3 (OTF-3); PO5F1_MOUSE;

Rabbit

A synthesized peptide derived from human Oct 4: 20-48

IgG

Liquid

affinity purified by Protein A

Recombinant

6B9

39 kDa

1mg/ml

10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.

Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

OCT4B-190蛋白能够增强细胞在应激条件下抵抗凋亡的能力。OCT4基因在干细胞的增殖、分化、应激反应、凋亡过程等多个生物学过程中发挥着重要的作用。

Expression of the POU-domain transcription factor Octamer-4 (Oct-4) is widely regarded as a hallmark of pluripotent stem cells. The relationship of Oct-4 to pluripotent stem cells is indicated by its tightly restricted expression to undifferentiated pluripotent stem cells. Upon differentiation to somatic lineages, the expression of Oct-4 disappears rapidly. Unlike the majority of pluripotent stem cell markers, the biological role of Oct-4 has been well characterized. Studies performed in mice point to the critical role of Oct-4 in the establishment and/or maintenance of pluripotent stem cells in an uncommitted state.