β分泌酶重组兔单抗

bsm-63071R

重组兔单抗

BACE1 Recombinant Rabbit mAb

β分泌酶重组兔单抗

ASP2; BACE; HSPC104; BACE1_HUMAN; BACE1; Aspartyl protease 2 (ASP2 | Asp 2); Beta-site amyloid precursor protein cleaving enzyme 1 (Beta-site APP cleaving enzyme 1); Memapsin-2; Membrane-associated aspartic protease 2; 3.4.23.46; KIAA1149; BACE1_MOUSE; BACE1_RAT;

Rabbit

A synthesized peptide derived from human BACE1: 450-501

IgG

Liquid

affinity purified by Protein A

Recombinant

13F6

56 kDa

1mg/ml

10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.

Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein(APP) by two proteases, one of which is the protein encoded by this gene. The encoded protein, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease that is found mainly in the Golgi. Multiple transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq].