肾小球裂孔膜蛋白PDCN重组兔单抗

bsm-63061R

重组兔单抗

NPHS2 Recombinant Rabbit mAb

肾小球裂孔膜蛋白PDCN重组兔单抗

PDCN; SRN1; podocin; PODO_HUMAN; NPHS2; PODO_MOUSE; PODO_RAT;

Rabbit

A synthesized peptide derived from human Podocin: 344-383

IgG

Liquid

affinity purified by Protein A

Recombinant

11B19

42 kDa

1mg/ml

10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.

Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

Podocin is an important member of a group of proteins shown to be associated with the slit diaphragm. Podocin belongs to the band 7 stomatin family of lipid raft-associated proteins. It is a hairpin like integral membrane protein with intracellular N and C termini. Podocin is located at the insertion site of the slit membrane, and is thought to act as a scaffold protein required to maintain or regulate the structural integrity of the slit diaphragm. It plays a role in the regulation of glomerular permeability, acting probably as a linker between the plasma membrane and the cytoskeleton.