胞质接头蛋白Keap1重组兔抗体

bsm-60935R

重组兔单抗

KEAP1 Recombinant Rabbit mAb

胞质接头蛋白Keap1重组兔抗体

INrf2; KLHL19; mKIAA0132; KEAP1_HUMAN; KEAP1; Cytosolic inhibitor of Nrf2 (INrf2); Kelch-like protein 19; KIAA0132; KEAP1_MOUSE; KEAP1_PIG; KEAP1_RAT;

Rabbit

KLH conjugated synthetic peptide derived from human KEAP1

IgG

Liquid

affinity purified by Protein A

Recombinant

7B13

69 kDa

1mg/ml

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

Keap1是细胞抗氧化反应的重要调节蛋白，Keap1与Nrf2/ARE构成的信号通路在抗肿瘤、抗应激、调节GSH合成、抗凋亡、抗炎反应、神经保护等方面发挥着广泛的细胞保护作用。

This gene encodes a protein containing KELCH-1 like domains, as well as a BTB/POZ domain. Kelch-like ECH-associated protein 1 interacts with NF-E2-related factor 2 in a redox-sensitive manner and the dissociation of the proteins in the cytoplasm is followed by transportation of NF-E2-related factor 2 to the nucleus. This interaction results in the expression of the catalytic subunit of gamma-glutamylcysteine synthetase. Two alternatively spliced transcript variants encoding the same isoform have been found for this gene. [provided by RefSeq, Jul 2008].