乳铁蛋白重组兔单抗
Rrmab®兔单抗
货号：bsm-62892R
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概述
产品编号
bsm-62892R
产品类型
重组兔单抗
英文名称
Lactoferrin Recombinant Rabbit mAb
中文名称
乳铁蛋白重组兔单抗
英文别名
GIG12; HEL110; HLF2; LF; Csp82; MMS10R; Ms10r; TRFL_HUMAN; LTF; Lactoferrin; Growth-inhibiting protein 12; Talalactoferrin; 3.4.21.-; TRFL_MOUSE;
抗体来源
Rabbit
免疫原
A synthesized peptide derived from human Lactoferrin: 650-710/710
亚型
IgG
性状
Liquid
纯化方法
affinity purified by Protein A
克隆类型
Recombinant
克隆号
19C8
理论分子量
78
检测分子量
78
储存液
10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
研究领域
SWISS
Gene ID
保存条件
Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles.
注意事项
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
数据库链接
背景资料
Transferrins are iron binding transport proteins which can bind two Fe3+ ions in association with the binding of an anion, usually bicarbonate.
产品应用
| 应用 | 已检合格种属 | 预测种属 | 推荐稀释比例 |
|---|---|---|---|
| WB | Human | 1:1000-5000 | |
| IHC-P | Human | 1:100-500 | |
| IHC-F | Human | 1:100-500 | |
| IF | Human | 1:100-500 | |
| IP | Human | 1:20-100 |
交叉反应
交叉反应: Human
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靶标
基因名
LTF
蛋白名
Lactotransferrin
亚基
Monomer. Found in a complex with LTF, CLU, EPPIN and SEMG1.
亚细胞定位
Isoform 1: Secreted. Isoform DeltaLf: Cytoplasm. Nucleus.
翻译后修饰
Isoform DeltaLf: Ubiquitinated at Lys-379 and Lys-391.
相似性
Belongs to the transferrin family.
Contains 2 transferrin-like domains.
Contains 2 transferrin-like domains.
功能
Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate.
Lactotransferrin has antimicrobial activity which depends on the extracellular cation concentration.
Lactoferroxins A, B and C have opioid antagonist activity. Lactoferroxin A shows preference for mu-receptors, while lactoferroxin B and C have somewhat higher degrees of preference for kappa-receptors than for mu-receptors.
The lactotransferrin transferrin-like domain 1 functions as a serine protease of the peptidase S60 family that cuts arginine rich regions. This function contributes to the antimicrobial activity.
Isoform DeltaLf: transcription factor with antiproliferative properties and inducing cell cycle arrest. Binds to DeltaLf response element found in the SKP1, BAX, DCPS, and SELH promoters.extracellular cation concentration.
Lactotransferrin has antimicrobial activity which depends on the extracellular cation concentration.
Lactoferroxins A, B and C have opioid antagonist activity. Lactoferroxin A shows preference for mu-receptors, while lactoferroxin B and C have somewhat higher degrees of preference for kappa-receptors than for mu-receptors.
The lactotransferrin transferrin-like domain 1 functions as a serine protease of the peptidase S60 family that cuts arginine rich regions. This function contributes to the antimicrobial activity.
Isoform DeltaLf: transcription factor with antiproliferative properties and inducing cell cycle arrest. Binds to DeltaLf response element found in the SKP1, BAX, DCPS, and SELH promoters.extracellular cation concentration.
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