phospho-MAP2 (Ser136) Recombinant Rabbit mAb (一抗) - IHC-P,IHC-F,IF,ICC/IF | Bioss
Rrmab?兔单抗
货号：bsm-62863R
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概述
产品编号
bsm-62863R
产品类型
磷酸化抗体、重组兔单抗、mIHC精品抗体
英文名称
phospho-MAP2 (Ser136) Recombinant Rabbit mAb
中文名称
磷酸化微管相关蛋白2重组兔单抗
英文别名
MAP2 (phospho-S136); p-MAP2; phospho-MAP2; MAP2 (phospho-Ser136); MAP-2; MAP2A; MAP2B; MAP2C; G1-397-34; Mtap-2; Mtap2; repro4; MAP2R; MTAP2_HUMAN; MAP2; MTAP2_MOUSE; MTAP2_RAT;
抗体来源
Rabbit
免疫原
A synthesized peptide derived from human MAP2 around the phosphorylation site of S136: NLPP-pS-PPP(全长1827aa)
亚型
IgG
性状
Liquid
纯化方法
affinity purified by Protein A
克隆类型
Recombinant
克隆号
19F17
理论分子量
200 kDa
检测分子量
70,280 kDa
储存液
10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
研究领域
SWISS
Gene ID
保存条件
Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles.
注意事项
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
数据库链接
产品介绍
微管相关蛋白 2（MAP-2)是一种磷蛋白质，在正常脑组织中，主要存在于神经元的胞体、树突和树突棘，是脑内最丰富的蛋白之一。MAP-2在其调节微管的聚合作用和微管的稳定性以及对神经元轴突和树突的发生、延长、稳定和突触可塑性调节具有重要作用。
背景资料
The exact function of MAP2 is unknown but MAPs may stabilize the microtubules against depolymerization. They also seem to have a stiffening effect on microtubules.
产品应用
| 应用 | 已检合格种属 | 预测种属 | 推荐稀释比例 |
|---|---|---|---|
| IHC-P | Human, Mouse, Rat | 1:100-200 | |
| IHC-F | Human, Mouse, Rat | 1:100-200 | |
| IF | Human, Mouse, Rat | 1:50-200 | |
| ICC/IF | Human, Mouse, Rat | 1:50-200 |
交叉反应
交叉反应: Human, Mouse, Rat
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暂无相关产品
靶标
基因名
MAP2
蛋白名
Microtubule-associated protein 2
亚细胞定位
Cytoplasm, cytoskeleton (Probable).
翻译后修饰
Phosphorylated at serine residues in K-X-G-S motifs by MAP/microtubule affinity-regulating kinase (MARK1 or MARK2), causing detachment from microtubules, and their disassembly (By similarity). MAP2A/c is phosphorylated. Isoform MAP2c is phosphorylated by FYN at Tyr-67.
相似性
Contains 3 Tau/MAP repeats.
功能
The exact function of MAP2 is unknown but MAPs may stabilize the microtubules against depolymerization. They also seem to have a stiffening effect on microtubules.
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