CRCP Recombinant Rabbit mAb (一抗) - WB,IHC-P,IHC-F,IF,IP | Bioss
Rrmab?兔单抗
货号：bsm-62756R
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概述
产品编号
bsm-62756R
产品类型
重组兔单抗
英文名称
CRCP Recombinant Rabbit mAb
中文名称
降钙素基因相关肽受体CRCP重组兔单抗
英文别名
C17; CGRP-RCP; CGRPRCP; POLR3I; POLR3J; RCP; RCP9; RPC9; RPC9_HUMAN; CRCP; RNA polymerase III subunit C9; Calcitonin gene-related peptide-receptor component protein (CGRP-RCP | CGRP-receptor component protein | CGRPRCP | HsC17);
抗体来源
Rabbit
免疫原
A synthesized peptide derived from human CRCP: 10-60
亚型
IgG
性状
Liquid
纯化方法
affinity purified by Protein A
克隆类型
Recombinant
克隆号
11D9
理论分子量
17 kDa
检测分子量
20 kDa
储存液
10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
研究领域
Cardiovascular > Heart > Contractility > Inotropics
Cardiovascular > Vasculature > Vasodilation
Neuroscience > Neurotransmission > Receptors / Channels > GPCR > More GPCR
Neuroscience > Neurotransmitter > Neuropeptides > Hormones
Neuroscience > Neurotransmitter > Neuropeptides > More Neuropeptides
Signal Transduction > Signaling Pathway > G Protein Signaling > GPCR
SWISS
Gene ID
保存条件
Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles.
注意事项
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
背景资料
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.
产品应用
| 应用 | 已检合格种属 | 预测种属 | 推荐稀释比例 |
|---|---|---|---|
| WB | Human, Mouse | Rat | 1:500-2000 |
| IHC-P | Human | Mouse, Rat | 1:50-200 |
| IHC-F | Human | Mouse, Rat | 1:50-200 |
| IF | Human | Mouse, Rat | 1:50-200 |
| IP | Human, Mouse, Rat | 1:20-50 |
交叉反应
交叉反应: Human, Mouse (predicted: Rat)
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靶标
基因名
CRCP
蛋白名
DNA-directed RNA polymerase III subunit RPC9
亚细胞定位
Nucleus. Cell membrane.
组织特异性
Ubiquitous. Most prevalent in testis.
相似性
Belongs to the eukaryotic RPC9 RNA polymerase subunit family.
功能
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts induce type I interferon and NF- Kappa-B through the RIG-I pathway.
Accessory protein for the calcitonin gene-related peptide (CGRP) receptor. It modulates CGRP responsiveness in a variety of tissues.
Accessory protein for the calcitonin gene-related peptide (CGRP) receptor. It modulates CGRP responsiveness in a variety of tissues.
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