TNFAIP8 Recombinant Rabbit mAb (一抗) - WB | Bioss
Rrmab?兔单抗
货号：bsm-62731R
产品详情
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常见问题
概述
产品编号
bsm-62731R
产品类型
重组兔单抗
英文名称
TNFAIP8 Recombinant Rabbit mAb
中文名称
肿瘤坏死因子α诱导蛋白8重组兔单抗
英文别名
GG2-1; MDC-3.13; NDED; SCC-S2; SCCS2; E130304C20Rik; Gm10539; Ssc-2; Tipe; TFIP8_HUMAN; TNFAIP8; TNF alpha-induced protein 8; Head and neck tumor and metastasis-related protein; NF-kappa-B-inducible DED-containing protein (NDED); TNF-induced protein GG2-1; TFIP8_MOUSE;
抗体来源
Rabbit
免疫原
A synthesized peptide derived from human TNFAIP8: 1-35
亚型
IgG
性状
Liquid
纯化方法
affinity purified by Protein A
克隆类型
Recombinant
克隆号
10H12
理论分子量
23 kDa
检测分子量
19-21 kDa
储存液
10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
研究领域
SWISS
Gene ID
保存条件
Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles.
注意事项
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
数据库链接
背景资料
Acts as a negative mediator of apoptosis and may play a role in tumor progression. Suppresses the TNF-mediated apoptosis by inhibiting caspase-8 activity but not the processing of procaspase-8, subsequently resulting in inhibition of BID cleavage and caspase-3 activation.
产品应用
| 应用 | 已检合格种属 | 预测种属 | 推荐稀释比例 |
|---|---|---|---|
| WB | Human | 1:500-2000 |
交叉反应
交叉反应: Human
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靶标
基因名
TNFAIP8
蛋白名
Tumor necrosis factor alpha-induced protein 8
亚细胞定位
Cytoplasm.
组织特异性
Expressed at high levels in the spleen, lymph node, thymus, thyroid, bone marrow and placenta. Expressed at high levels both in various tumor tissues, unstimulated and cytokine-activated cultured cells. Expressed at low levels in the spinal cord, ovary, lung, adrenal glands, heart, brain, testis and skeletal muscle.
相似性
Belongs to the TNFAIP8 family.
功能
Acts as a negative mediator of apoptosis and may play a role in tumor progression. Suppresses the TNF-mediated apoptosis by inhibiting caspase-8 activity but not the processing of procaspase-8, subsequently resulting in inhibition of BID cleavage and caspase-3 activation.
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