PTPRR Recombinant Rabbit mAb (一抗) - WB | Bioss

bsm-62713R

重组兔单抗

PTPRR Recombinant Rabbit mAb

蛋白酪氨酸磷酸酶受体PCPTP1重组兔单抗

PCPTP1; EC-PTP; PTP-SL; PTPBR7; PTPRQ; Gmcp1; RPTPRR; mPTP213; PC12-PTP1; R-PTP-R; PTPRR_HUMAN; PTPRR; Ch-1PTPase; NC-PTPCOM1; Protein-tyrosine phosphatase PCPTP1; 3.1.3.48; ECPTP; PTPRR_MOUSE; Phosphotyrosine phosphatase 13; Protein-tyrosine-phosphatase SL; Ptp13; protein tyrosine phosphatase receptor type R

Rabbit

A synthesized peptide derived from human PTPRR: 25-50

IgG

Liquid

affinity purified by Protein A

Recombinant

4A12

74 kDa

70 kDa

10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.

Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles.

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

Sequesters mitogen-activated protein kinases (MAPKs) such as MAPK1, MAPK3 and MAPK14 in the cytoplasm in an inactive form. The MAPKs bind to a dephosphorylated kinase interacting motif, phosphorylation of which by the protein kinase A complex releases the MAPKs for activation and translocation into the nucleus (By similarity).

PTPRR

Receptor-type tyrosine-protein phosphatase R

Interacts with MAPKs

Cell membrane and Cytoplasm > perinuclear region. Locates to the perinuclear areas within the cytoplasm.

Expressed in brain, placenta, small intestine, stomach, uterus and weakly in the prostate. Isoform alpha has been observed only in the brain. Isoform gamma is expressed in brain, placenta and uterus. Isoform delta is expressed in brain, kidney, placenta, prostate, small intestine and uterus.

Belongs to the protein-tyrosine phosphatase family. Receptor class 7 subfamily.
Contains 1 tyrosine-protein phosphatase domain.

Sequesters mitogen-activated protein kinases (MAPKs) such as MAPK1, MAPK3 and MAPK14 in the cytoplasm in an inactive form. The MAPKs bind to a dephosphorylated kinase interacting motif, phosphorylation of which by the protein kinase A complex releases the MAPKs for activation and translocation into the nucleus.