蛋白酪氨酸磷酸酶受体PCPTP1重组兔单抗

Rrmab®兔单抗
2026-01-04~2026-02-28,RR26012026-01-04~2026-02-28,TR
蛋白酪氨酸磷酸酶受体PCPTP1重组兔单抗
货号:bsm-62713R
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概述

产品编号
bsm-62713R
产品类型
重组兔单抗
英文名称
PTPRR Recombinant Rabbit mAb
中文名称
蛋白酪氨酸磷酸酶受体PCPTP1重组兔单抗
英文别名
PCPTP1; EC-PTP; PTP-SL; PTPBR7; PTPRQ; Gmcp1; RPTPRR; mPTP213; PC12-PTP1; R-PTP-R; PTPRR_HUMAN; PTPRR; Ch-1PTPase; NC-PTPCOM1; Protein-tyrosine phosphatase PCPTP1; 3.1.3.48; ECPTP; PTPRR_MOUSE; Phosphotyrosine phosphatase 13; Protein-tyrosine-phosphatase SL; Ptp13;
抗体来源
Rabbit
免疫原
A synthesized peptide derived from human PTPRR: 25-50
亚型
IgG
性状
Liquid
纯化方法
affinity purified by Protein A
克隆类型
Recombinant
克隆号
4A12
理论分子量
74
检测分子量
74
储存液
10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
SWISS
Gene ID
保存条件
Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles.
注意事项
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
背景资料
Sequesters mitogen-activated protein kinases (MAPKs) such as MAPK1, MAPK3 and MAPK14 in the cytoplasm in an inactive form. The MAPKs bind to a dephosphorylated kinase interacting motif, phosphorylation of which by the protein kinase A complex releases the MAPKs for activation and translocation into the nucleus (By similarity).
蛋白酪氨酸磷酸酶受体PCPTP1重组兔单抗

产品应用

应用已检合格种属预测种属推荐稀释比例
WBMouse, RatHuman1:500-2000

交叉反应

交叉反应: Mouse, Rat (predicted: Human)

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靶标

基因名
PTPRR
蛋白名
Receptor-type tyrosine-protein phosphatase R
亚基
Interacts with MAPKs
亚细胞定位
Cell membrane and Cytoplasm > perinuclear region. Locates to the perinuclear areas within the cytoplasm.
组织特异性
Expressed in brain, placenta, small intestine, stomach, uterus and weakly in the prostate. Isoform alpha has been observed only in the brain. Isoform gamma is expressed in brain, placenta and uterus. Isoform delta is expressed in brain, kidney, placenta, prostate, small intestine and uterus.
相似性
Belongs to the protein-tyrosine phosphatase family. Receptor class 7 subfamily.
Contains 1 tyrosine-protein phosphatase domain.
功能
Sequesters mitogen-activated protein kinases (MAPKs) such as MAPK1, MAPK3 and MAPK14 in the cytoplasm in an inactive form. The MAPKs bind to a dephosphorylated kinase interacting motif, phosphorylation of which by the protein kinase A complex releases the MAPKs for activation and translocation into the nucleus.

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