GRP78/Bip Recombinant Rabbit mAb (一抗) - IHC-P,IHC-F,IF,ICC/IF | Bioss

Name: 葡萄糖调节蛋白78重组兔单抗（GRP78/Bip Recombinant Rabbit mAb）
Brand: 北京博奥森生物科技有限公司
SKU: bsm-62645R
Availability: InStock

Rrmab^?兔单抗

2026-07-01~2026-08-31，AB2607A 京东卡2026-07-01~2026-08-31，AB2607B 豪礼卡

一键复制说明书

货号：bsm-62645R

产品详情

概述

产品编号

bsm-62645R

产品类型

重组兔单抗

英文名称

GRP78/Bip Recombinant Rabbit mAb

中文名称

葡萄糖调节蛋白78重组兔单抗

英文别名

BIP; GRP78; HEL-S-89n; BIP_HUMAN; HSPA5; 78 kDa glucose-regulated protein (GRP-78); Binding-immunoglobulin protein (BiP); Heat shock protein 70 family protein 5 (HSP70 family protein 5); Heat shock protein family A member 5; Immunoglobulin heavy chain-binding protein; 3.6.4.10; heat shock protein family A (Hsp70) member 5; heat shock 70kD protein 5 (glucose-regulated protein, 78kD); heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa); glucose-regulated protein, 78kDa

抗体来源

Rabbit

免疫原

A synthesized peptide derived from human GRP78 BiP: 600-654

亚型

IgG

性状

Liquid

纯化方法

affinity purified by Protein A

克隆类型

Recombinant

克隆号

9D16

理论分子量

72 kDa

检测分子量

78 kDa

储存液

10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.

研究领域

Tags & Cell Markers > Subcellular Markers > Organelles > ER

SWISS

P11021

Gene ID

3309

保存条件

Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles.

注意事项

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

数据库链接

Entrez Gene : 3309 Human

SwissProt : P11021 Human

产品介绍

葡萄糖调节蛋白78是热休克蛋白70家族的成员之一，又称：热休克蛋白70蛋白5,作为一种分子伴侣在蛋白质的折叠和转运过程及内质网应激反应中发挥重要作用.它在多种肿瘤组织中呈高表达.

背景资料

Endoplasmic reticulum chaperone that plays a key role in protein folding and quality control in the endoplasmic reticulum lumen. Involved in the correct folding of proteins and degradation of misfolded proteins via its interaction with DNAJC10/ERdj5, probably to facilitate the release of DNAJC10/ERdj5 from its substrate.

基因名

HSPA5

蛋白名

Endoplasmic reticulum chaperone BiP

亚细胞定位

Endoplasmic reticulum lumen. Melanosome. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.

疾病

Note=Autoantigen in rheumatoid arthritis.

相似性

Belongs to the heat shock protein 70 family.

功能

Probably plays a role in facilitating the assembly of multimeric protein complexes inside the ER.