葡萄糖调节蛋白78重组兔单抗

bsm-62645R

重组兔单抗

GRP78/Bip Recombinant Rabbit mAb

葡萄糖调节蛋白78重组兔单抗

BIP; GRP78; HEL-S-89n; BIP_HUMAN; HSPA5; 78 kDa glucose-regulated protein (GRP-78); Binding-immunoglobulin protein (BiP); Heat shock protein 70 family protein 5 (HSP70 family protein 5); Heat shock protein family A member 5; Immunoglobulin heavy chain-binding protein; 3.6.4.10;

Rabbit

A synthesized peptide derived from human GRP78 BiP: 600-654

IgG

Liquid

affinity purified by Protein A

Recombinant

9D16

72

78

10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.

Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles.

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

葡萄糖调节蛋白78是热休克蛋白70家族的成员之一，又称：热休克蛋白70蛋白5,作为一种分子伴侣在蛋白质的折叠和转运过程及内质网应激反应中发挥重要作用.它在多种肿瘤组织中呈高表达.

Endoplasmic reticulum chaperone that plays a key role in protein folding and quality control in the endoplasmic reticulum lumen. Involved in the correct folding of proteins and degradation of misfolded proteins via its interaction with DNAJC10/ERdj5, probably to facilitate the release of DNAJC10/ERdj5 from its substrate.