肌球蛋白调节轻链12B重组兔单抗

Rrmab®兔单抗
2026-01-04~2026-02-28,RR26012026-01-04~2026-02-28,TR
肌球蛋白调节轻链12B重组兔单抗
货号:bsm-62539R
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概述

产品编号
bsm-62539R
产品类型
重组兔单抗、mIHC精品抗体
英文名称
MYL12B Recombinant Rabbit mAb
中文名称
肌球蛋白调节轻链12B重组兔单抗
英文别名
MRLC2; MLC-B; 1500001M02Rik; Mylc2b; RLC-B; Mrlcb; ML12B_BOVIN; MYL12B; Myosin regulatory light chain 2-B, smooth muscle isoform; Myosin regulatory light chain 20 kDa (MLC20); Myosin regulatory light chain MRLC2; ML12B_HUMAN; MLC-2A (MLC-2); SHUJUN-1; ML12B_MOUSE; ML12B_RAT; Myosin RLC-B; Myosin regulatory light chain 2-B, smooth muscle isoform (MLC-2);
抗体来源
Rabbit
免疫原
A synthesized peptide derived from human Myosin light chain 12B: 150-172
亚型
IgG
性状
Liquid
纯化方法
affinity purified by Protein A
克隆类型
Recombinant
理论分子量
20
检测分子量
18
储存液
10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
SWISS
Gene ID
保存条件
Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles.
注意事项
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
背景资料
Myosin regulatory subunit that plays an important role in regulation of both smooth muscle and nonmuscle cell contractile activity via its phosphorylation. Phosphorylation triggers actin polymerization in vascular smooth muscle. Implicated in cytokinesis, receptor capping, and cell locomotion.
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产品应用

应用已检合格种属预测种属推荐稀释比例
WBHuman, Mouse, Rat1:500-2000
IHC-PHuman, Mouse, Rat1:100-500
IHC-FHuman, Mouse, Rat1:100-500
IFHuman, Mouse, Rat1:100-500
ICC/IFHuman, Mouse, Rat1:50-200

交叉反应

交叉反应: Human, Mouse, Rat

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靶标

基因名
MYL12B
蛋白名
Myosin regulatory light chain 12B
组织特异性
Ubiquitously expressed in various hematopoietic cells.
翻译后修饰
Phosphorylation increases the actin-activated myosin ATPase activity and thereby regulates the contractile activity. It is required to generate the driving force in the migration of the cells but not necessary for localization of myosin-2 at the leading edge. Phosphorylation is reduced following epigallocatechin-3-O-gallate treatment.
相似性
Contains 3 EF-hand domains.
功能
Myosin regulatory subunit that plays an important role in regulation of both smooth muscle and nonmuscle cell contractile activity via its phosphorylation. Phosphorylation triggers actin polymerization in vascular smooth muscle. Implicated in cytokinesis, receptor capping, and cell locomotion.

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