Protein-disulfide reductase of the endoplasmic reticulum that promotes disulfide bond formation in client proteins through its thiol-disulfide oxidase activity.
产品应用
应用
已检合格种属
预测种属
推荐稀释比例
WB
Human
Mouse, Rat
1:500-2000
IHC-P
Human, Mouse, Rat
1:50-200
IHC-F
Human, Mouse, Rat
1:50-200
IF
Human, Mouse, Rat
1:50-200
ICC/IF
Human, Mouse, Rat
1:50-200
交叉反应
交叉反应: Human, Mouse, Rat
相关产品
暂无相关产品
靶标
基因名
TXNDC12
蛋白名
Thioredoxin domain-containing protein 12
亚细胞定位
Endoplasmic reticulum.
组织特异性
Widely expressed.
相似性
Contains 1 thioredoxin domain.
功能
ERp19 belongs to the thioredoxin superfamily. Members of this superfamily possess a thioredoxin fold with a consensus active-site sequence (CxxC) and have roles in redox regulation, defense against oxidative stress, refolding of disulfide-containing proteins, and regulation of transcription factors. Possesses significant protein thiol-disulfide oxidase activity.