脂肪酸去饱和酶1重组兔单抗
Rrmab®兔单抗
货号：bsm-62440R
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概述
产品编号
bsm-62440R
产品类型
重组兔单抗
英文名称
FADS1 Recombinant Rabbit mAb
中文名称
脂肪酸去饱和酶1重组兔单抗
英文别名
D5D; FADS6; FADSD5; LLCDL1; TU12; 0710001O03Rik; A930006B21Rik; DSD; FADS1_HUMAN; FADS1; Delta(5) fatty acid desaturase (D5D | Delta(5) desaturase | Delta-5 desaturase); Fatty acid desaturase 1; 1.14.19.44; FADS1_MOUSE; FADS1_RAT;
抗体来源
Rabbit
免疫原
A synthesized peptide derived from human FADS1: 100-140
亚型
IgG
性状
Liquid
纯化方法
affinity purified by Protein A
克隆类型
Recombinant
克隆号
17H18
理论分子量
52
检测分子量
52
储存液
10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
研究领域
Cancer > Cancer Metabolism > Metabolic signaling pathway > Metabolism of lipids and lipoproteins
Cardiovascular > Lipids / Lipoproteins > Fatty Acids > Synthesis
Metabolism > Pathways and Processes > Metabolic signaling pathways > Lipid and lipoprotein metabolism > Lipid metabolism
Metabolism > Pathways and Processes > Redox metabolism > Fatty acid oxidation
Metabolism > Types of disease > Cancer
SWISS
Gene ID
保存条件
Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles.
注意事项
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
数据库链接
背景资料
Acts as a front-end fatty acyl-coenzyme A (CoA) desaturase that introduces a cis double bond at carbon 5 located between a preexisting double bond and the carboxyl end of the fatty acyl chain.
产品应用
| 应用 | 已检合格种属 | 预测种属 | 推荐稀释比例 |
|---|---|---|---|
| IHC-P | Human | 1:100-500 | |
| IHC-F | Human | 1:100-500 | |
| IF | Human | 1:100-500 | |
| Flow-Cyt | Human | 1ug/Test | |
| ICC/IF | Human | 1:50-200 |
交叉反应
交叉反应: Human
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靶标
基因名
FADS1
蛋白名
Acyl-CoA(8-3)-desaturase
亚细胞定位
Endoplasmic reticulum membrane; Multi-pass membrane protein
组织特异性
Expressed in many tissues, it is most abundant in the liver, brain, adrenal gland and heart. Found as well in skeletal muscle, lung, placenta, kidney, pancreas and retina.
相似性
Belongs to the fatty acid desaturase family.
Contains 1 cytochrome b5 heme-binding domain
Contains 1 cytochrome b5 heme-binding domain
功能
Component of a lipid metabolic pathway that catalyzes biosynthesis of highly unsaturated fatty acids (HUFA) from precursor essential polyunsaturated fatty acids (PUFA) linoleic acid (LA) (18:2n-6) and alpha-linolenic acid (ALA) (18:3n-3). Catalyzes the desaturation of dihomo-gamma-linoleic acid (DHGLA) (20:3n-6) and eicosatetraenoic acid (20:4n-3) to generate arachidonic acid (AA) (20:4n-6) and eicosapentaenoic acid (EPA)(20:5n-3) respectively.
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