ACSL4 Recombinant Rabbit mAb (一抗) - WB,IHC-P,IHC-F,IF,IP | Bioss

bsm-62432R

重组兔单抗、mIHC精品抗体

ACSL4 Recombinant Rabbit mAb

酰基辅酶A合成酶4重组兔单抗

ACS4; FACL4; LACS4; MRX63; MRX68; XLID63; 9430020A05Rik; ACSL4_HUMAN; ACSL4; Arachidonate--CoA ligase; Long-chain acyl-CoA synthetase 4 (LACS 4); 6.2.1.3; ACSL4_MOUSE; Long-chain acyl-CoA synthetase 4 (LACS 4 | mACS4); ACSL4_RAT; acyl-CoA synthetase long chain family member 4; fatty-acid-Coenzyme A ligase, long-chain 4; mental retardation, X-linked 63; mental retardation, X-linked 68; lignoceroyl-CoA synthase; long-chain fatty-acid-Coenzyme A ligase 4

Rabbit

A synthesized peptide derived from human ACSL4: 650-691

IgG

Liquid

affinity purified by Protein A

Recombinant

1G12

79 kDa

75 kDa

10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.

Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles.

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

ACSL4

Long-chain-fatty-acid--CoA ligase 4

Mitochondrion outer membrane. Peroxisome membrane. Microsome membrane. Endoplasmic reticulum membrane.

Defects in ACSL4 are the cause of mental retardation X-linked type 63 (MRX63) [MIM:300387]. Mental retardation is a mental disorder characterized by significantly sub-average general intellectual functioning associated with impairments in adaptative behavior and manifested during the developmental period. Non-syndromic mental retardation patients do not manifest other clinical signs.
Defects in ACSL4 are involved in Alport syndrome with mental retardation midface hypoplasia and elliptocytosis (ATS-MR) [MIM:300194]. A X-linked contiguous gene deletion syndrome characterized by glomerulonephritis, deafness, mental retardation, midface hypoplasia and elliptocytosis.

Belongs to the ATP-dependent AMP-binding enzyme family.

Activation of long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation. Preferentially uses arachidonate and eicosapentaenoate as substrates.