NUP62 Recombinant Rabbit mAb (一抗) | Bioss

bsm-62402R

重组兔单抗

NUP62 Recombinant Rabbit mAb

核孔糖蛋白P62重组兔单抗

IBSN; SNDI; p62; D7Ertd649e; Nupc1; Np62; NUP62_HUMAN; NUP62; 62 kDa nucleoporin; Nucleoporin Nup62; NUP62_MOUSE; NUP62_RAT; nucleoporin 62; nucleoporin 62kDa; nuclear pore glycoprotein p62

Rabbit

A synthesized peptide derived from human NUP62: 481-522

IgG

Liquid

affinity purified by Protein A

Recombinant

9F19

53 kDa

62 kDa

10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.

Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles.

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

The nuclear pore complex is a structure that extends across the nuclear envelope and regulates the flow of macromolecules between the cytoplasm and the nucleus. Nucleoporins are the main components of the nuclear pore complex in eukaryotic cells.

NUP62

Nuclear pore glycoprotein p62

Component of the p62 complex, a complex at least composed of NUP62, NUP54, and NUPL1 (By similarity). Interacts with C11orf73/Hikeshi.

Nucleus, nuclear pore complex. Cytoplasm, cytoskeleton, spindle pole. Note=Central region of the nuclear pore, within the transporter. During mitotic cell division, it associates with the poles of the mitotic spindle.

O-glycosylated. Contains about 10 N-acetylglucosamine side chain sites predicted for the entire protein, amongst which only one in the C-terminal.

Infantile striatonigral degeneration (SNDI) [MIM:271930]: Neurological disorder characterized by symmetrical degeneration of the caudate nucleus, putamen, and occasionally the globus pallidus, with little involvement of the rest of the brain. The clinical features include developmental regression, choreoathetosis, dystonia, spasticity, dysphagia, failure to thrive, nystagmus, optic atrophy, and mental retardation. Note=The disease is caused by mutations affecting the gene represented in this entry.

Belongs to the nucleoporin NSP1/NUP62 family.

Essential component of the nuclear pore complex. The N-terminal is probably involved in nucleocytoplasmic transport. The C-terminal is probably involved in protein-protein interaction via coiled-coil formation and may function in anchorage of p62 to the pore complex.