Prokineticin 1 Recombinant Rabbit mAb (一抗) - WB,Flow-Cyt | Bioss

bsm-62397R

重组兔单抗

Prokineticin 1 Recombinant Rabbit mAb

内分泌腺衍生血管内皮生长因子重组兔单抗

EGVEGF; PK1; PRK1; EG-VEGF; PROK1_HUMAN; PROK1; Endocrine-gland-derived vascular endothelial growth factor (EG-VEGF); Mambakine; PROK1_MOUSE; PROK1_RAT; prokineticin 1; black mamba toxin-related protein; Endocrine gland-derived vascular endothelial growth factor

Rabbit

A synthesized peptide derived from human PROK1: 1-105

IgG

Liquid

affinity purified by Protein A

Recombinant

2A8

12 kDa

12 kDa

10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.

Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles.

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

EG-VEGF是先被发现的组织特异性促血管生成因子,与多种特定组织肿瘤的发生及演进相关，EG-VEGF多在卵巢、睾丸、肾上腺、胎盘等类固醇合成组织中高表达。

Potently contracts gastrointestinal (GI) smooth muscle. Induces proliferation, migration and fenestration (the formation of membrane discontinuities) in capillary endothelial cells derived from endocrine glands.

PROK1

Prokineticin-1

Secreted.

Localizes to glandular epithelium, stroma and vascular epithelial cells of first trimester decidua (at protein level). Up-regulated in first trimester decidua when compared with non-pregnant endometrium. Expressed in the steroidogenic glands, ovary, testis, adrenal and placenta.

Belongs to the AVIT (prokineticin) family.

Potently contracts gastrointestinal (GI) smooth muscle. Induces proliferation, migration and fenestration (the formation of membrane discontinuities) in capillary endothelial cells derived from endocrine glands. Has little or no effect on a variety of other endothelial and non-endothelial cell types. Induces proliferation and differentiation, but not migration, of enteric neural crest cells. Directly influences neuroblastoma progression by promoting the proliferation and migration of neuroblastoma cells. Positively regulates PTGS2 expression and prostaglandin synthesis. May play a role in placentation. May play a role in normal and pathological testis angiogenesis.