Growth factor active on keratinocytes. Possible major paracrine effector of normal epithelial cell proliferation.
基因名
FGF7
蛋白名
Fibroblast growth factor 7
亚基
Interacts with FGFBP1. Interacts with FGFR2. Affinity between fibroblast growth factors (FGFs) and their receptors is increased by heparan sulfate glycosaminoglycans that function as coreceptors.
亚细胞定位
Secreted.
组织特异性
Epithelial cell.
相似性
Belongs to the heparin-binding growth factors family.
功能
Plays an important role in the regulation of embryonic development, cell proliferation and cell differentiation. Required for normal branching morphogenesis. Growth factor active on keratinocytes. Possible major paracrine effector of normal epithelial cell proliferation.