肠型脂肪酸结合蛋白重组兔单抗
Rrmab®兔单抗
货号：bsm-62307R
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概述
产品编号
bsm-62307R
产品类型
重组兔单抗
英文名称
IFABP Recombinant Rabbit mAb
中文名称
肠型脂肪酸结合蛋白重组兔单抗
英文别名
FABPI; I-FABP; FABP; FABPI_HUMAN; FABP2; Fatty acid-binding protein 2; Intestinal-type fatty acid-binding protein (I-FABP); FABPI_MOUSE; FABPI_RAT;
抗体来源
Rabbit
免疫原
A synthesized peptide derived from human Fatty acid binding protein 2: 1-45/132
亚型
IgG
性状
Liquid
纯化方法
affinity purified by Protein A
克隆类型
Recombinant
克隆号
1D8
理论分子量
15
检测分子量
15
储存液
10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
研究领域
Cardiovascular > Lipids / Lipoproteins > Fatty Acids > Binding proteins
Cardiovascular > Lipids / Lipoproteins > Fatty Acids > Metabolism
Developmental Biology > Lineage specification > Endoderm
Metabolism > Pathways and Processes > Metabolic signaling pathways > Lipid and lipoprotein metabolism > Fatty acids
Metabolism > Pathways and Processes > Redox metabolism > Fatty acid oxidation
SWISS
Gene ID
保存条件
Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles.
注意事项
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
数据库链接
产品介绍
小肠脂肪酸结合蛋白(IFABP)主要是在小肠分泌的一种蛋白质,参与了脂肪酸的吸收和代谢。IFABP有可能通过干扰脂肪酸代谢而影响胰岛素敏感性。
IFABP主要用于2型糖尿病相关性的研究。
IFABP主要用于2型糖尿病相关性的研究。
背景资料
FABPs are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters. FABP2 is probably involved in triglyceride-rich lipoprotein synthesis. Binds saturated long-chain fatty acids with a high affinity, but binds with a lower affinity to unsaturated long-chain fatty acids.
产品应用
| 应用 | 已检合格种属 | 预测种属 | 推荐稀释比例 |
|---|---|---|---|
| WB | Mouse, Rat | Human | 1:500-2000 |
| IHC-P | Human, Mouse, Rat | 1:100-500 | |
| IHC-F | Human, Mouse, Rat | 1:100-500 | |
| IF | Human, Mouse, Rat | 1:100-500 |
交叉反应
交叉反应: Human, Mouse, Rat
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靶标
基因名
FABP2
蛋白名
Fatty acid-binding protein, intestinal
亚细胞定位
Cytoplasm.
组织特异性
Expressed in the small intestine and at much lower levels in the large intestine. Highest expression levels in the jejunum.
相似性
Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
功能
FABP are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters. FABP2 is probably involved in triglyceride-rich lipoprotein synthesis. Binds saturated long-chain fatty acids with a high affinity, but binds with a lower affinity to unsaturated long-chain fatty acids. FABP2 may also help maintain energy homeostasis by functioning as a lipid sensor.
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